实验性暗区对多焦视觉诱发电位的影响  

Effect of experimental scotoma on multifocal visual evoked potential

作　　者：胡晓鹏[1] 黄时洲[2] 江福钿[2] 龙时先[2] 梁炯基[2] 吴德正[2] 吴乐正[2] 

机构地区：[1]重庆医科大学附属第二医院眼科,重庆400010 [2]中山大学中山眼科中心,广州510060

出　　处：《第三军医大学学报》2007年第7期629-631,共3页Journal of Third Military Medical University

摘　　要：目的探讨实验性暗区对多焦视觉诱发电位的影响。方法应用VERIS Science 4.0视觉诱发反应图像系统对10例(20只眼)正常人进行mf-VEP检测,每例受试者在同一测试时间共进行6次测试,左右眼各3次。右眼分别进行全视野测试和遮盖上半视野、遮盖下半视野测试;左眼分别进行全视野测试和遮盖中央3环视野、遮盖鼻下1/4视野测试。通过VERIS软件分析mf-VEP的二阶一次反应,并对不同视野区域遮盖前后的mf-VEP分区进行比较。结果所有受试者mf-VEP在遮盖的视野区域出现振幅反应密度或振幅总和反应明显降低,潜伏期延长不明显,部分波形呈平坦型;在未遮盖的大部分视野区域振幅反应密度无变化,仅局部区域下降,统计学检验有显著性差异(P<0.05)。结论mf-VEP可发现实验性暗区的影响,其改变与视野具有对应一致性,可以用于临床检测,但在分析时应根据不同的情况划分不同的区域进行比较。Objective To investigate the influence of experimental scotoma on muhifocal visual evoked potential （mf-VEP）. Methods The mf-VEP of 10 healthy individuals （20 eyes） was measured with VERIS Science 4.0. Every eye was measured for 3 times. The tight eye was measured with full field stimulation and upper hemi-field or lower hemi-field masked. The left eye was measured with full field stimulation and central three-rings area or lower nasal field masked. The first slice responses of the second order in different field were analyzed and compared by VERIS software. Results The mf-VEP in masked area was undetectable or obviously decreased in all subjects. In most unmasked field, the amplitudes of mf-VEP were not changed, except that in some place decreased slightly with statistically significant difference in comparison to the full field stimulation mode. Conclusion mf-VEP is influenced with experimental scotoma. The mf-VEP changes are consistent with the visual field masked.

关 键 词：多焦视觉诱发电位 实验性暗区 正常人 

分 类 号：R339.141[医药卫生—人体生理学] R339.145[医药卫生—基础医学]