大鼠三叉神经节内含内吗啡肽2的神经元向延髓背角投射  

AXON-PROJECTION OF ENDOMORPHIN-2-CONTAINING NEURONS IN THE TRIGEMINAL GANGLION TO THE MEDULLARY DORSAL HORN IN THE RAT

作　　者：廖衡[1] 陈涛[1] 李云庆[1] 

机构地区：[1]第四军医大学基础部人体解剖学教研室梁琚脑研究中心,西安710032

出　　处：《解剖学报》2007年第2期241-242,共2页Acta Anatomica Sinica

基　　金：国家自然科学基金资助项目(30370458)

摘　　要：目的观察大鼠三叉神经节(TG)内的内吗啡肽2(EM2)阳性神经元向延髓背角(MDH)的投射情况。方法荧光金(FG)追踪与EM2免疫荧光组织化学染色相结合的双标方法。结果将FG注入MDH后,TG内可见大量FG标记的大、中、小型神经元;TG内也可见各种直径的EM2阳性神经元;TG内的许多FG标记神经元呈EM2阳性,FG/EM2双标神经元多为中、小型神经元。结论TG内的EM2阳性神经元向MDH投射。Objective To observe whether endomorphin-2-immunoreactive （EM2-ir） neurons in the trigeminal ganglion （TG） project to the medullary dorsal horn （MDH） in the rat. Methods Fluoro-gold （FG） retrograde tracing and immunofluorescent histochemical staining for EM2 were applied. Results After FG was injected into the MDH, many FG labeled neurons with small, medium and large diameters were observed in the TG. There were also aboundant EM2-ir neurons with different diameters in the TG. The majority of FG labeled neurons in the TG showed EM2-immunoreactivities. Almost all of the EM2/FG double-labeled neurons were medium and small in size. Conclusion EM2-ir neurons in the TG project to the MDH in the rat.

关 键 词：内吗啡肽 延髓背角 三叉神经节 痛 免疫荧光 大鼠 

分 类 号：R322.8[医药卫生—人体解剖和组织胚胎学]