多巴胺在FcA/Nafion/GCE上的电化学行为及其SWV测定应用  

Electrochemical Behaviors of Dopamine at FcA/Nafion/GCE and Its Determination Application by SWV

作　　者：马艳蓉[1] 高作宁[1] 

机构地区：[1]宁夏大学能源化工重点实验室,宁夏银川750021

出　　处：《宁夏大学学报（自然科学版）》2007年第1期45-48,共4页Journal of Ningxia University(Natural Science Edition)

基　　金：教育部科研重点基金资助项目(204149);宁夏高等学校科研基金资助项目(200623)

摘　　要：研究了多巴胺（Dopamine，DA）在二茂铁乙酸（Ferrocenyl Acetic Acid，FcA）和Nation聚合物薄膜修饰玻碳电极（FcA／Nation／GCE）上的电化学行为，测定了DA在该修饰电极上的动力学参数，并用方波伏安法（SWV）对DA在FcA／Nation／GCE上的测定应用进行了研究．结果表明，与GCE相比，DA在FcA／Nation／GCE上的峰电流增大约10倍，氧化峰电位负移60mV，表明FcA／Nation／GCE对DA有良好的电化学催化作用；同时测得DA在FcA／Nation／GCE上的电子转移系数口为0．44，反应速率常数k。为0．106cm／s，表观扩散系数D0为5．4×10^-6cm^2／s．用SwV方法测得DA浓度在1．0×10^-5～2．0×10^-3mol／L范围内氧化峰电流（Jpa）与其呈良好的线性关系，线性拟舍方程为Jpa（μA）=47．524＋16．508c（10mol／L），相关系数R=0．9989，检出限为1．0×10^-6mol／L，相对标准偏差为0．9％～1．1％，回收率为97．5％～100．1％．该测定方法简单快捷，测定结果令人满意．The electrochemical parameters were determined. behaviors of dopamine（DA） at FcA/Nafion/GCE were studied and the kinetics The experimental results showed that FcA/Nafion/GCE showed an excellent electrocatalytic activity for DA. The peak current increased about 10 times and the oxidation peak potentials shifted negatively 60 mV for DA at FcA/Nafion/GCE than GCE. The electron transfer coefficient and the electrode reaction rate constant of DA on FcA/Nafion/GCE are 0.44 and 0. 106 cm/s, respectively. The diffusion coefficient is 5. 4 × 10^-6 cm^2/s. relationship in the concentration The catalytic current of DA vs. its concentration had a good linear range between 1.0 × 10^-5 mol/L and 2.0 × 10^-3 mol/L by SWV. The correlation coefficient is 0. 998 9. DA concentration in commercial injection samples was determined. The relative standard deviation is between 0.9% and 1.1% and recovery is in the range between 97.5% and 100.1% with the detection limit of 1.0× 10^-6 mol/L. The determination results are satisfactory.

关 键 词：二茂铁乙酸 NATION 修饰电极 多巴胺 方波伏安法 

分 类 号：O657[理学—分析化学]