广州市钩端螺旋体病血清流行病学调查  

The epidemiological factor investigation on the natural infection of leptospirosis disease in Guangzhou city

作　　者：陈小霜[1] 罗雷[1] 刘海涛[1] 陈志强[2] 许晓茵[3] 梁振波[4] 吴志辉[5] 利朴良 李中有[7] 

机构地区：[1]广州市疾病预防控制中心传染病防制科,广州510080 [2]广州市白云区疾病预防控制中心 [3]广州市番禺区疾病预防控制中心 [4]广州市花都区疾病预防控制中心 [5]广州市天河区疾病预防控制中心 [6]从化市疾病预防控制中心 [7]增城市疾病预防控制中心

出　　处：《中国媒介生物学及控制杂志》2007年第2期141-143,共3页Chinese Journal of Vector Biology and Control

摘　　要：目的了解广州市钩端螺旋体病(钩体病)重点流行区域流行病学概况。方法用现场流行病学调查方法和血清学检测,对钩体病重点流行区域内健康人群和相关宿主动物进行检测;采用显微镜凝集试验检测抗体。结果对808份健康人群血清标本及727份鼠血清标本进行检测,发现健康人群钩体抗体阳性率为7.30%(59/808),各调查点人群性别间阳性率差异有统计学意义(χ2=6.487,P<0.05);水网及旱地间人群发病率差异亦有统计学意义(χ2=8.068,P<0.01);鼠类阳性率平均为0.55%,其中褐家鼠为0.47%,黄胸鼠为3.17%。结论钩体病重点流行区域内健康人群和野鼠中存在钩体隐性感染,其感染幅度与该地区钩体病的发病有一定的相关作用。Objective To probe the epidemiological features of the natural infection of leptospirosis disease in Guangzhou. Methods The serum of healthy people and host animal in the focus was collected and the serological detection and field epidemiological investigation were carried out. The status of carrying germ in that area was analyzed and evaluated. Results The antibody positive rate among 808 healthy people was 7.30 % （59/808）. The difference of positive rate among different sample spots was significan（χ^2 = 6.487, P〈 0.05）; The difference of positive rate between dry land and flatness area was significant（χ^2 = 8. 068, P〈 0.01 ） as well. The positive rate of rats was 0.55 % , R. norvegicus 0.4796 and R. flavipectus 3.17% seperately. Conclusion The resalts of serological detection and epidemiologlcal investigation indicated that the focus existed strictly. The level of infection rate among healthy people and host animal was related to the incidence of leptospira disease in that area.

关 键 词：钩端螺旋体病 血清抗体检测 流行病学调查 

分 类 号：R377.5[医药卫生—病原生物学]