某高校学生乙型肝炎病毒感染动态变化研究  

Study on dynamic status of hepatitis B virus infection in university students

作　　者：刘劼[1] 蒋德勇[2] 

机构地区：[1]南华大学病原生物学研究所,湖南衡阳421001 [2]四川省攀枝花市疾病预防控制中心

出　　处：《中国校医》2007年第2期137-138,共2页Chinese Journal of School Doctor

摘　　要：目的调查大学生HBsAg的携带率,以及大学生在校期间HBsAg携带状况的动态变化,为大学生乙型肝炎病毒的预防提供理论依据。方法对某高校2000级大学生进行两次体检,即新生入校体检和毕业生体检,抽取静脉血,ELISA法检测HBsAg,采用SPSS13.0进行统计学分析。结果共调查6244人,新生HBsAg携带率为5.7%,新生HBsAg携带率不存在性别、专业和地区差异;毕业生总的HBsAg携带率为13.8%,医学专业的毕业生HBsAg携带率显著高于非医学专业的毕业生,男性毕业生显著高于女性。HBsAg阴转率为7.3%。结论大学生在校期间可能感染乙型肝炎病毒,大学生是乙型肝炎病毒预防的重点人群。Objective To investigate the status of HBsAg carrier in college students and the change during the college period, so as to provide the theoretical basis for hepatitis B virus （HBV） prevention, Methods Physical examination and laboratory tests were carried out in new students and graduate students of Grade 2000 in a university. HBsAg was tested by enzyme-linked immunosorbent assay （ELISA）. Statistic analysis was conducted with SPSS 13.0. Results A total of 6 244 students were surveyed and the rate o f HBsAg carrier in new students was 5.7 % （358/ 6 244）. There were no significant difference between the genders, between the specialties and between the districts in the new students, P 〉0.05. The rate o f HBsAg carrier in graduate students was 13.8%. In the graduate students, the rate of HBsAg carrier in medical students was significantly higher than that in other specialty students, P 〈 0.05, and the rate of HBsAg carrier in male was significantly higher than that in female, P〈 0.05. There were 26 HBsAg carriers becoming negative among 358 HBsAg carriers （7 . 3 % ）. Conclusions College students may be infected with HBV during their college period, and they are the important population of HBV prevention.

关 键 词：乙肝表面抗原 学生保健服务 

分 类 号：R183.9[医药卫生—流行病学]