降龙搽剂质量标准研究  

Study on Quality Standards for Xianglong Liniment

作　　者：马金刚[1,2] 李迎雁[3] 赵兴红[4] 

机构地区：[1]兰州大学药学院 [2]兰州军区联勤部药品仪器检验所,兰州市730000 [3]兰州军区兰州总医院药材科 [4]兰州军区联勤部药品仪器检验所

出　　处：《中国药房》2007年第12期921-923,共3页China Pharmacy

摘　　要：目的：建立降龙搽剂的质量标准.方法：采用薄层色谱法鉴别方中冰片;采用高效液相色谱法同时测定龙血素A和B的含量.结果：在薄层色谱中可检出冰片的特征斑点,阴性对照无干扰.龙血素A、B分别在0.2～3.0 μg和0.05～0.70 μg范围内,进样量与峰面积呈良好线性关系;龙血素A、B的平均回收率分别为99.3%（RSD=2.02%）、95.2%（RSD=1.75%）.结论：本文所建标准可用于降龙搽剂的质量控制.OBJECTIVE： To establish the quality standards for Xianglong liniment. METHODS： Borneol was identified with TLC, and the contents of Loureirin A and B in Xianglong liniment were determined with HPLC. RESULTS： The spots characteristic of Borneol were found through TLC detection, with no interference seen against negative control. There was a good linear relationships between sample sizes and peak areas when Loureirin A and B were in respective ranges of 0.2-3.0μg and 0.05-0.70μg. The average recovery of loureirin A was 99.3% with RSD of 2.02%, and that of loureirin B was 95.2% with RSD of 1.75% .CONCLUSION：The standard can be used for the quality control of Xianglong liniment.

关 键 词：降龙搽剂 冰片 龙血素A 龙血素B 薄层色谱法 高效液相色谱法 

分 类 号：R927.1[医药卫生—药学] R286