大鼠淋巴结树突状细胞的超微结构研究  

Ultrastructural Studies on Dendritic Cell of Lymph Node in Rat

作　　者：苏丽英[1] 康文华[1] 袁德霞[1] 李淑荣[1] 宋金忠[2] 

机构地区：[1]河北医科大学组胚教研室,石家庄050017 [2]河北医科大学第五附属医院,石家庄050017

出　　处：《中华物理医学杂志》1996年第2期96-98,T011,12,共5页Chinese Journal of Physical Medicine and Rehabilitation

摘　　要：应用电镜及细胞化学技术,观察大鼠淋巴结树突状细胞的超微结构及5′-核苷酸酶的反应。发现有两种形态和分布树突状细胞,即小结树突细胞和交错突细胞。小结树突细胞是见于淋巴小结内一种形状不规则,具有多突的细胞;突起的形状呈多样性且与周围淋巴细胞关系密切,5′-核苷酸酶呈阳性反应。交错突细胞位于副皮质区内,其超微结构特征为细胞一侧的细长指状折叠的突起、大形线粒体及其周围单层排列的粗面内质网;5′-核苷酸酶呈阴性反应。两种树突状细胞形态分布各异,因此其免疫辅佐机能也不尽相同。Ultrastructure and 5'-nucleotidase reation of dendritic cell of rat lymphatic nodes were studied by electron microscope and cytochemical technique. Two kinds of DC different in morphology and distribution were found: follicular dendritic cell and interdigitating cell. The follicalar dendritic cell located in lymphatic follicle with irregular shape and multiple processes. The process was various in shape and related closely with peripheral lymphocytes. The 5'-nucleotidase reation of the cell was positive. The interdigitating cell located in the deep cortex. The ultrastructure showed long thin finger-like interdigitating processes in one side of the cell, large mitochondria and single layer rough endoplasmic reticulum in periphery. The 5'-nucleotidase reation of the cell was negative. The two kind cells were quite different in morphology and distribution and this provided different ageing effect in the immunity.

关 键 词：小结树突细胞 交错突细胞 5′-核苷酸酶 淋巴结 大鼠 

分 类 号：R322.25[医药卫生—人体解剖和组织胚胎学] R361.3[医药卫生—基础医学]