维生素C治疗伤口愈合的临床应用进展  

The Clinical Development of Vitamin C in Wound Healing

作　　者：王仙凤[1] 梁楠[2] 张晓[2] 

机构地区：[1]成都医学院 [2]成都医学院实验技术教研室,四川成都610083

出　　处：《西南军医》2007年第2期79-80,共2页Journal of Military Surgeon in Southwest China

基　　金：成都医学院院长基金资助(05Z2005-009)

摘　　要：维生素C是一种抗菌氧化剂,具有保护细胞膜及亚细胞器,增加机体免疫功能,促进全面组织修复的炎性趋化作用。所有伤口在环境污染和理化作用下都会产生大量氧自由基,氧自由基使毛细胞管壁通透性增高,血管内皮细胞损伤,加重受伤区邻近组织的缺血、水肿、缺氧,造成更广泛的细胞死亡和组织溶解等一系列继发损伤。维生素C能参与胶原蛋白和组织细胞间质的合成,改善毛细血管壁的通透性,不仅能促进新鲜组织生成,减少渗出,而且能够促进创面的愈合。因此,维生素C在治疗伤口愈合作用上具有广阔的前景。Vitamin C,an antibacterial oxidant,can strengthen the body＇s immune abihty,and promote inflammatory chemotaxis function of all the tissue. All wounds can bring forth lots of oxygen free radicals under the polluted circumstance and the function of physics and chemistry. The oxygen free radicals have the function of improving the permeability of capillary, injuring the endothelial cell of vas, aggravating ischemia,edema and hypoxia of the wound tissue. Vitamin C takes part in compounding the collagenous protein and interstitial histiocyte,changing permeability of the wall of capillary. It not only renews tissue and reduces exudation,but also accelerates the velocity of wound healing. In a word,there will be a bright future.

关 键 词：维生素C 伤口愈合 

分 类 号：R977.23[医药卫生—药品]