不同方式招募的吸毒者高危行为和HIV、HCV及梅毒感染的比较  

Comparison of High Risk Behaviors,the Prevalence of HIV、HCV and Syphilis among Drug Users Enrolled through Different Recruitment Methods in Xichang County of Sichuan Province, China

作　　者：宋洪琼[1] 陈曦[2] 阮玉华[2] 宋本莉[1] 梁姝[3] 李新旭[2] 张莉[4] 尹潞[2] 陈康林[1] 秦光明[3] 邵一鸣 

机构地区：[1]西昌市皮肤病性病防治站,四川615000 [2]中国疾病预防控制中心性病艾滋病预防控制中心 [3]四川省疾病预防控制中心 [4]中国协和医科大学协和公共卫生学院

出　　处：《中国自然医学杂志》2007年第1期6-9,共4页Chinese Journal of Natural Medicine

基　　金：卫生部艾滋病防治应用性研究项目(WA2003-13);国家十五科技攻关项目(2004BA719A01);国家自然科学基金项目(30571612;10501052)资助

摘　　要：目的比较不同方式招募的吸毒者社会人口学、高危行为及HIV、HCV和梅毒感染情况。方法于2004年5-7月，从四川省凉山彝族自治州西昌市社区中招募吸毒人群调查其社会人口学特征、近3个月直接和间接共用注射器具静脉吸毒方式、近6个月性行为情况。采集研究对象的血样进行HIV、HCV和梅毒抗体检测。结果在招募的451名吸毒者中，通过同伴招募和其他方式招募的分别占73．8％和26．2％。性别、民族、年龄、文化程度和婚姻状况在不同方式招募的吸毒者中差异有统计学意义。静脉注射吸毒频率、口吸海洛因频率、海洛因混合其他毒品使用频率、共用针头或注射器频率、共用洗针头或注射器用水频率、共用吸毒器皿频率、共用棉球频率、共用注射器前或后装入毒品频率、以及与固定性伴／临时性伴非保护性性行为、以性交为条件给性伙伴提供钱物和新的性伙伴在不同方式招募的吸毒者中差异有统计学意义。未见不同方式招募的吸毒者HIV、HCV和梅毒感染差异有统计学意义。结论应答驱动抽样是招募吸毒人员的有效方法，通过同伴容易招募到少数民族和高危行为的吸毒者。Objective To study differences of socio - demography, high risk sex behaviors, the prevalence of HIV, HCV and syphilis infection among drug users enrolled through different recruitment methods of respondent-driven sampling. Methods From May 21304 to July 21304, a cross-sectional survey was conducted to investigate socio- demographic characteristics, direct and indirect sharing of injection equipment in the past three months and sexual behaviors in the past six months among drug users. Blood samples were also collected to test for HIV, HCV and syphilis antibodies. Results Of the 451 drug users, those who were enrolled through peer referral and others were 73.8% and 26.2%, respectively. Gender, minority, age, marital status, sharing of needle or syringe, sharing of cooker, sharing of cotton, sharing of rinse water and sharing of front- or hack- loading in the past 3 months, tmprotected sex behavior and gave money for sex in the past month, were fotmd statistically significant differences among different samples, respectively. HIV, HCV and syphilis infection were fotmd to be no significant statistical differences between different recruitment methods respectively. Conclusion Respondent - driven sampling is a effective recruitment method. Minority and drug users at high risk can be recruited through peer referral.

关 键 词：同伴 招募 吸毒 高危行为 HIV HCV 梅毒 

分 类 号：R512.91[医药卫生—内科学]