参冬清凉喉片的质量标准研究  

Quality Standard for Shendong Qingliang Hou Tablets

作　　者：张素芬[1] 邓鸣[1] 田四琦[1] 

机构地区：[1]解放军白求恩国际和平医院药剂科,石家庄050082

出　　处：《华北国防医药》2007年第2期70-72,F0003,共4页Medical Journal of Beijing Military Region

摘　　要：目的：建立参冬清凉喉片的质量标准。方法：采用薄层色谱法对处方中玄参、麦冬及甘草进行定性鉴别。以高效液相色谱法测定黄芩中黄芩苷的含量。结果：薄层斑点清晰，重现性好；黄芩苷在6—60μg／ml范围内线性关系良好（r=0．9999），平均回收率为101．87％，相对标准偏差（RSD）为0．68％。结论：本方法简便、准确、专属性强、重现性好，可有效地控制参冬清凉喉片的质量。Objective ：To establish the quality standard for Shendong Hou tablets. Methods ： Radix Serophulariae, Radix Ophiopogonis, and Radix et Rhizoma Glyeyrrhizae in Shendong Hou tablets were identified by TLC. Baiealin in Radix Seutellariae was determined by HPLC. Resuits：The characteristics for identification by TLC were distinct. The calibration curve of baiealin was linear within 6 - 60μg/ml （r = 0.9999 ）. The average recovery and RSD were 101.87% ,0.68%. Conclusion：The method is simple, accurate closely related, and with good repeatability. It can control the quality of this preparation effectively.

关 键 词：植物制剂 质量控制 色谱法 薄层 黄芩苷 

分 类 号：R943.3[医药卫生—药剂学]