药物致急性肾功能衰竭47例临床分析  

Clinnical analysis of 47 cases with acute renal failure caused by medicine

作　　者：金晓冰[1] 何新生[1] 高国胜[1] 

机构地区：[1]湖北省鄂州市中心医院肾内科,鄂州436000

出　　处：《华中医学杂志》2007年第2期119-120,共2页Central China Medical Journal

摘　　要：目的总结药物致急性肾功能衰竭(ARF)的临床特点及治疗经验。方法回顾分析47例药物致ARF患者的临床特点及疗效。结果老年组32例(68.1%),少尿型ARF患者21例,少尿时间为(10±4)天,24例需血液透析治疗,死亡4例;青年组15例(31.9%),少尿型ARF患者5例,少尿时间为(7±4)天,6例需血液透析治疗,1例患者死亡。两组共治愈37例,转为慢性肾功能衰竭(CRF)5例,5例死亡。结论药物致ARF老年人发病率及病死率均高于青年人。内科综合治疗联合血液净化治疗疗效好,对抢救ARF具有重要意义。Objective To investigate the clinical feature and summarize the therapy of acute renal failure（ARF） caused by medicine. Methods Retrospective analysis was on 47 patients with ARF caused by medicine in resent 5 years. Results There were 32 patients in old group（total 68.1%）, among which 21patients were uropenia patients, uropenia time was （10 ± 4） days, and 24 patients needed dialysis, 4 patients were died. In youth group which has 15 patients, 5 patients were uropenia patients, uropenia time was （7 ± 4） days,6 patients needed dialysis, only one was died. 37 patients were cured of two groups, 5 patients changed into ehronieal failure（CRF）and 5 patients were died. Conclusion Both the incidence and mortality rate of ARF caused by medicine in the elderly are higher than the youth. Intergrative medicine therpy combining hemodilalysis is a superior method for the treatment of ARF caused by medicine.

关 键 词：肾功能衰竭 急性 药物 血液净化 

分 类 号：R595.3[医药卫生—内科学]