丙酸絮凝发酵新工艺研究  

Study on A New Method of Propionic Acid Flocculated Fermentation

作　　者：王丽丽[1] 仪宏[1] 赵紫华[1] 

机构地区：[1]河北科技大学生物科学与工程学院,石家庄050018

出　　处：《微生物学通报》2007年第2期300-302,共3页Microbiology China

基　　金：国家"十五"科技攻关资助项目(No2001BA708B05-04)

摘　　要：报道了丙酸发酵的一种新工艺:絮凝发酵工艺。采用谢氏丙酸杆菌(Propionibacterium shermanii)W125在批次发酵产酸达到29g/L的基础上,选择氢氧化钙作为中和剂兼絮凝剂,建立了絮凝半连续发酵工艺,连续运行250h,产酸量达到了35.4g/L,产酸率提高了22%,糖酸转化率达到了51.56%,体积效率达到了0.37g/(L/h)。This paper reports the flocculated fermentation as a new method of prepionic acid production. Propionibacterium shermanii W125 were used, 29. Og/L prepionic acid was accumulated in batch fermentation. In the subsequently established fed batch semicontinous fermentation, 35.4g/L propionic acid was accumulated, raised to 122% and the conversion rate of glucose to prepionic acid reached 51.56%, the volumetric productivity reached 0. 37g/ （L/h） during the 250 hours ruaning cycle.

关 键 词：丙酸发酵 絮凝发酵 半连续发酵 

分 类 号：TQ225.1[化学工程—有机化工]