脉压增高的原发性高血压患者的临床分析  

Clinical characteristic of essential hypertensive patients with high pulse pressure

作　　者：张明华[1] 刘国树[1] 吕丽英[2] 

机构地区：[1]解放军总医院南楼心血管二科,北京市100853 [2]解放军总医院门诊内科,北京市100853

出　　处：《心血管康复医学杂志》2007年第2期134-136,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:研究脉压增高的原发性高血压患者的动脉硬化指数、血液生化指标及一般情况的临床特点,探讨其临床意义。方法:随机对解放军总医院门诊原发性高血压患者进行血压、脉压、动脉硬化指数的测定,并检测患者的血尿酸、血糖、血脂、肌酐、尿素氮等血液生化指标及一般情况,总计133例,按照患者的脉压分为2组。正常脉压组:102例,脉压小于60mmHg。高脉压组:31例,脉压大于或等于60mmHg。对2组患者进行对照比较。结果:(l)脉压增高的原发性高血压患者的年龄、病史和收缩压显著高于正常脉压者,而其舒张压显著低于正常脉压者(P均<0.01);(2)脉压增高的原发性高血压患者的动脉硬化指数(P<0.01)、血尿酸(P<0.05)水平显著增高。结论:脉压增大的原发性高血压患者的临床特点为年龄大、病史长、收缩压升高、舒张压降低,动脉硬化程度较重,并伴有血尿酸水平升高。Objective： To investigate the clinical characteristic of essential hypertensive （EH） patients with high pulse pressure. Methods： A total of 133 EH patients were recruited randomly in the outpatient department of high blood pressure of the General Hospital of PLA. The patients were divided into two groups according to their pulse pressure levels： control group （n=102）, with the pulse pressure lower than 60 mmHg; high pulse pressure group （n=31）, with the pulse pressure≥60 mmHg. The demographic characteristics, arterial stiffness index （ASI） and blood pa- rameters were measured and compared between the two groups. Results： There were older age, longer hypertensive history, higher systolic blood pressure （SBP）, but lower diastolic blood pressure （DBP）, （ P〈0. 01 all） in the high pulse pressure group than those of control group. The ASI （P〈0. 01） and the level of blood uric acid （P〈0. 05） were higher in the high pulse pressure group than those of control group. Conclusion： Old age, long hypertensive history. higher SBP pressure, lower DBP. higher levels of ASI and blood uric acid may be associated with EH patients with high pulse pressure.

关 键 词：高血压 动脉硬化 尿酸 

分 类 号：R544.1[医药卫生—心血管疾病]