RE(C_7H_5O_3)_2(C_9H_6NO)配合物抗真菌作用的热动力学研究  被引量:19

Thermokinetics Study of Antifungal Functions of Complexes of Rare Earths with Salicylic Acid and 8-Hydroxyquinoline

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作  者:何笃贵[1] 李强国[1] 杨德俊[1] 李旭[1] 叶丽娟[1] 魏得良[1] 黄熠[1] 张辉[1] 刘义[1] 

机构地区:[1]湘南学院化学与生命科学系,湖南郴州423000

出  处:《中国稀土学报》2007年第1期107-110,共4页Journal of the Chinese Society of Rare Earths

基  金:湖南省自然科学基金资助项目(03JJY3019)

摘  要:应用微量热法研究了配合物RE(C7H5O3)2(C9H6NO)(RE代表La,Sm和Nd)对真菌的抗菌作用。在TAM Air热导式等温微量量热仪上,分别测定了桔青霉菌和黑曲霉菌在不同浓度不同稀土配合物及空白条件下生长代谢热谱曲线,并计算得到了真菌在不同条件下的生长代谢速率常数κ和传代时间G等热动力学参数。实验表明:3种稀土水杨酸8-羟基喹啉三元配合物对桔青霉菌和黑曲霉菌均有抑制作用,其抑制效果依次为:Sm(Hsal)2(hq)>La(Hsal)2(hq)>Nd(Hsal)2(hq)。To research into the antifungal functions of RE ( C7H5 O3) 2 (CaH6NO), the thermokinetie properties of antifungal functions of RE ( C7H5O3 )2 ( CaH6NO ) complexes to Penicillium cityinum Thorn and Aspergillus niger were studied by the microcalorimetric method. Thermograms on growth metabolism of the epiphyte were determined at different concentration and for different complexes. The growth rate constants and generation times were obtained respectively. Experimental results show that all the complexes Sm(Hsal)2 (hq), Nd(Hsal)2(hq) and La(Hsal)2(hq) have inhibitive function, and the inhibitory effectiveness of Sm (Hsal)2(hq), Nd(Hsal)2(hq) and La(Hsal)2(hq) is the order of Sm(Hsal)2(hq) 〉 La(Hsal)2(hq) 〉 Nd (Hsal)2(hq).

关 键 词:稀土配合物 抗真菌作用 热谱曲线 生长速率常数 

分 类 号:O641.4[理学—物理化学] O614.33[理学—化学]

 

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