Wavelength dependence of soft tissue ablation by using pulsed lasers  

作　　者：张先增 谢树森 叶青 詹振林 

机构地区：[1]Key Laboratory of Optoelectronic Science and Technology for Medicine of Ministry of Education Fujian Normal University [2]Fujian Medical University

出　　处：《Chinese Optics Letters》2007年第4期235-237,共3页中国光学快报（英文版）

基　　金：This work was supported by the National Natural Science Foundation of China (No.60578057);the Fujian Provincial Education Scientific Project (No.JAO50217/JB06108).

摘　　要：Pulsed laser ablation of soft biological tissue was studied at 10.6-, 2.94-, and 2.08-μm wavelengths. The ablation effects were assessed by means of optical microscope, the ablation crater depths were measured with reading microscope. It was shown that Er：YAG laser produced the highest quality ablation with clear, sharp cuts following closely the spatial contour of the incident beam and the lowest fluence threshold. The pulsed CO2 laser presented the moderate quality ablation with the highest ablation efficiency. The craters drilled with Ho：YAG laser were generally larger than the incident laser beam spot, irregular in shape, and clearly dependent on the local morphology of biotissue. The ablation characteristics, including fluence threshold and ablation efficiency, varied substantially with wavelength. It is not evident that water is the only dominant chromophore in tissue.Pulsed laser ablation of soft biological tissue was studied at 10.6-, 2.94-, and 2.08-μm wavelengths. The ablation effects were assessed by means of optical microscope, the ablation crater depths were measured with reading microscope. It was shown that Er：YAG laser produced the highest quality ablation with clear, sharp cuts following closely the spatial contour of the incident beam and the lowest fluence threshold. The pulsed CO2 laser presented the moderate quality ablation with the highest ablation efficiency. The craters drilled with Ho：YAG laser were generally larger than the incident laser beam spot, irregular in shape, and clearly dependent on the local morphology of biotissue. The ablation characteristics, including fluence threshold and ablation efficiency, varied substantially with wavelength. It is not evident that water is the only dominant chromophore in tissue.

关 键 词：CHROMOPHORES Laser ablation Laser beams Laser pulses MORPHOLOGY Optical microscopy TISSUE 

分 类 号：R318.6[医药卫生—生物医学工程] TN249[医药卫生—基础医学]