102株解脲支原体耐药分析  

Study on infections and drug resistance of mycoplasma in female vaginalis.

作　　者：于志军[1] 孙悦波[1] 韩志梅[1] 

机构地区：[1]大连市友谊医院检验科,辽宁大连116001

出　　处：《临床和实验医学杂志》2007年第4期98-99,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的了解女性生殖道支原体感染及耐药状况,为临床治疗提供依据。方法采用美国其昌达公司支原体计数鉴定药敏试剂盒,对240份患者阴道分泌物进行支原体培养、鉴定及药物敏感试验。结果110份标本培养出支原体,总检出率为42.8%。其中单纯解脲支原体感染阳性例数为102例,阳性率为42.5%;解脲支原体合并人型支原体感染例数为6例,阳性率为2.5%;单纯人型支原体感染例数为2例,阳性率为0.8%。药敏结果表明解脲脲原体对强力霉素、米诺环素敏感性高达99%;大环内酯类除克拉霉素有较高的敏感性(85.9%)外,其余药物的敏感性均较低;喹诺酮类药物的耐药现象严重。结论在女性生殖道支原体感染中解脲脲原体是主要病原微生物,强力霉素和米诺环素是治疗阴道支原体感染的首选药物。Objective To survey infections and drug resistance of mycoplasma in female vaginalis, and provide laboratory evidence for clinical therapy. Methods 240 specimens from female vaginal discharge swab were detected by kit of Quick Da. Results From 240 tested samples, the total positive percentage for mycoplasma was 42.8%. The positive percentage of Ureaplasma urealyticum（ Uu）, Mycoplasma hominis （ Mh ） and mixed infections was 42.5% , 0.8% and 2.5% respectively. The sensitivity of Uu to antimicrobial agents was as follows from high to low： Doxycycline, Minocyeline, Clarithromyein, other maerolides, quinolones. Conclusion Uu was one of the most common pathogens in female vaginalis. Doxycycline and Minocycline were choice drugs against Uu.

关 键 词：解脲支原体 人型支原体 药物敏感试验 耐药性 

分 类 号：R711.3[医药卫生—妇产科学]