4种除杂工艺对红花水提物的除杂效果比较  

Study of four miscellaneous object ablation technologies on safflor yellow aqueous extract

作　　者：马依努尔.拜克力 吴桂荣[1] 王岩[1] 

机构地区：[1]新疆医科大学药学院,新疆乌鲁木齐830054

出　　处：《新疆医科大学学报》2007年第3期212-214,共3页Journal of Xinjiang Medical University

基　　金：新疆自然科学基金资助项目(2005211106)

摘　　要：目的:评价4种除杂工艺对红花黄色素水提物的除杂效果。方法:通过高效液相色谱法(high per-formance liquid chromatography,HPLC)测定红花水提物中羟基红花黄色素A的含量,以有效成分的含量及浸膏得率为指标,对大孔树脂法、澄清剂A、澄清剂B及乙醇沉淀4种除杂工艺进行比较。结果:优化除杂工艺为:水提液浓缩比例1∶3,3%的澄清剂B,絮凝150min。结论:红花水提物提取工艺可用澄清剂替代乙醇。Objective： To evaluate the effectiveness of four miscellaneous object ablation technologies on safflor yellow aqueous extract. Methods： Contents of hydroxy safflor yellow A in the safflor yellow aqueous extract was determined through HPLC method. A comparative study was performed among four kinds of ablation technologies, contents of active ingredient and received residue were selected as comparison indexes. Results： Aqueous extract concentrated to 1 ： 3 and 3% clarifying agent B was added to the aqueous extract, the time needed for flocculate was 150 minutes was turned out to be the optimal method. Conclusion： Clarifying agents could be substitude for alcohol.

关 键 词：红花 羟基红花黄色素-A HPLC 

分 类 号：R943[医药卫生—药剂学] Q949.783[医药卫生—药学]