更昔洛韦治疗先天性巨细胞病毒感染疗效观察  

Clinical Therapeutic Effect of Ganciclovir on Neonatal Congenital Cytomegalovirus Infection

作　　者：董淮富[1] 潘家华[2] 李莉[1] 李兴武[3] 

机构地区：[1]安徽省蚌埠医学院第一附属医院儿科,233004 [2]安徽省立医院儿科,合肥230022 [3]安徽省蚌埠医学院第一附属医院检验科,233004

出　　处：《实用全科医学》2007年第5期396-397,共2页Applied Journal Of General Practice

摘　　要：目的观察更昔洛韦治疗先天性巨细胞病毒感染的临床疗效。方法将先天性巨细胞病毒感染患儿随机分为病毒唑治疗组(26例)及更昔洛韦治疗组(27例),对两组患儿的临床表现及治疗效果进行观察。结果结果显示,病毒唑治疗组和更昔洛韦治疗组疗程结束后,在临床表现、实验室检查及病毒学结果转归方面进行比较,差异均有统计学意义(P<0.05)。结论更昔洛韦对先天性巨细胞病毒感染有显著疗效,且副作用小,值得临床推广。Objective To observe the clinical therapeutic effects of Ganeielovir on neonatal congenital Cytomegalovirus （CMV） infeetionMethods 53 infants with congenital CMV infection were randomly divided into virazole group （26cases） and Ganeielovir group （27cases） , clinical performance and therapeutic effects were compared. Results There were significantly differences in clinical performance, laboratory examination and virology test result between virazole group and Ganeielovir group in posttreatment （ P 〈0. 05 ）. Conclusions Ganeielovir is effective on neonatal congenital CMV infection with littler side-effect, so it can be spread in clinical practice.

关 键 词：更昔洛韦 先天性 巨细胞病毒 

分 类 号：R512.5[医药卫生—内科学]