丝裂霉素C联合前房维持器在青光眼滤过性手术中的应用  

The anterior chamber maintainer combination with mitomycin in glaucoma filtertin operation

作　　者：黄贤[1] 李艳[1] 黄经河[2] 叶舒[2] 罗文玲[1] 邓全好[1] 

机构地区：[1]广西贵港市人民医院,贵港537100 [2]广西医科大学第八附属医院眼科

出　　处：《中国实用眼科杂志》2007年第2期165-166,共2页Chinese Journal of Practical Ophthalmology

摘　　要：目的探讨青光眼滤过性手术中应用前房维持器（ACM）联合丝裂霉素对手术效果的影响。方法35例（49眼）患者随机分为MMC＋ACM组和对照组，对照组用传统小梁切除术MMC＋ACM组在传统小梁切除术中应用MMC后，经前房穿刺置入ACM，根据液体渗漏情况缝合巩膜瓣。结果MMC＋ACM组术后眼压控制有效率为92．59％，功能性滤泡占88．89％。2眼（7．4％）出现浅前房；对照组控制眼压有效率68．18％，功能性滤泡12眼（54．55％），8眼（36．37％）出现前前房，两组间差异均具有统计学意义（13〈0．05），两组手术前后视力无明显变化。结论联合ACM和MMC应用于青光眼滤过器手术，可以延长滤过泡功能，减少瘢痕形成，并减少低眼压出现，提高滤过性手术的成功率。Objective To evaluate the effect of anterior chamber maintainer （ACM） combined with Mitomycin （MMC） in glaucoma filtering operation. Methods 35 patients （49eyes） were divide randomly to MMC＋ACM group and control group. The filtering operation is finished as routine in control group while in MMC＋ACM group, MMC cotton slice placed under conjunctiva and sclera flap, then put ACM through puncture of anterior chamber. Result Postoperatively, in MMC＋ACM group, the controlled ratio of intraocular pressure is 92.59%, and the formation rate of the functional filtering bleb shallow anterior hamber are 88.89% and 36.37% respectively. Which in control group were 68.18%, 54.55% and 36.37%, respectively. There were significantly difference between the two groups（p〈0.05）. Conclusion The combination of ACM and MMC in the filtering operation can not only lengthen the function of the filtering bleb and decrease the scar, but also lowered intraocular pressure, then increase the successful ratio of filtering operation.

关 键 词：青光眼 滤过性手术 前房维持器 丝裂霉素C 

分 类 号：R457.1[医药卫生—治疗学]