核糖体失活蛋白的应用研究进展  

The Progress on Ribosome-Inactivating Proteins Application

作　　者：胡俊[1] 孙素荣[1] 张智[1] 兰海燕[1] 张富春[1] 

机构地区：[1]新疆大学生命科学与技术学院分子生物学重点实验室,新疆乌鲁木齐830046

出　　处：《新疆大学学报（自然科学版）》2007年第2期204-210,共7页Journal of Xinjiang University(Natural Science Edition)

摘　　要：核糖体失活蛋白(ribosome-inactivating proteins,RIPs)是一类广泛存在于高等植物中能抑制核糖体翻译功能的毒蛋白.本文就核糖体失活蛋白在抗病毒、抗真菌、抗昆虫、抗肿瘤及艾滋病等方面的研究进展及应用作一综述.Ribosome-inactivating protein （RIP） is a group of toxic proteins which can inhibit ribosome of its translation function by a specific modification in the large rRNA. It largely exists in higher plants. In this paper the research progress and the application of the RIP in many aspects, such as anti-virus, anti-fungus, anti-insect, anti-tumor and anti-HIV, are reviewed.

关 键 词：核糖体失活蛋白 抗病毒 抗真菌 抗昆虫 抗肿瘤 抗艾滋病 

分 类 号：Q78[生物学—分子生物学]