新型二正丁基锡(Ⅳ)羧酸酯的合成、晶体结构及杀菌活性研究  

Synthesis,Crystal Structure and Antibacterial Activity of Di-n-butyltin Carboxylate

作　　者：闫文华[1] 康万利[1] 李金环[1] 

机构地区：[1]大庆石油学院教育部采收率重点实验室,大庆163318

出　　处：《化学通报》2007年第4期313-316,共4页Chemistry

基　　金：黑龙江省杰出青年科学基金(J03-11);黑龙江省省教育厅(1055HZ034)资助项目

摘　　要：在苯溶液中,将2-(2-甲酰基-6-甲氧基苯氧基)乙酸与二正丁基氧化锡进行脱水反应,获得新型二正丁基锡(Ⅳ)羧酸酯(1),经过元素分析、1HNMR和IR及晶体结构测定等手段对其进行了结构表征。锡原子为五配位,构成以锡为中心的扭曲三角双锥构型,三个双锡氧环构成具有对称结构的二聚体。中心环[Sn2O2]通过氧原子与两个环外锡原子相连,双齿配体羧基的两个氧原子分别与环内和环外锡原子配位,每个环外锡原子还与羧基形成单齿配位。此外还初步研究了其杀菌活性。The compound （1） [systematic name： 1,2：3,4-di-μ2-2-（2-formyl-6-methoxyphenoxy）acetic-O,O-1,3- bis-2-（2-formyl-6-methoxyphenoxy）acetic- O-1,2,4：2,3,4-di-μ3-oxo-tetrakis[ di-n-butyltin（ Ⅳ ） ] ] was synthesized by the reactions of di-n-butyl tin oxide and 2-（2-formyl-6-methoxyphenoxy）acetic acid with azeotropic removal of water in the solvents of benzene. Tin was characterized by elemental analysis, 1H NMR, FT-IR spectroscopy and single crystal X-ray diffraction analysis. Three distannoxane tings are present to the dimer of planar ladder arrangement with distorted trigonalbipyramidal geometry about the five-coordinated tin centers. The structure, which has twofold symmetry, features a central Sn2O2 unit with two additional tin atoms linked at O. Pairs of tin atoms are bridged by bidentate carboxylate ligands and the external tin atoms have their coordination geometry completed by a monodentate carboxylate ligand. The antibacterial activity of compound 1 was preliminary studied.

关 键 词：有机锡(Ⅳ)2-(2-甲酰基-6-甲氧基苯氧基)乙酸 晶体结构杀菌活性 

分 类 号：TQ455[化学工程—农药化工]