用放射免疫分析法测定受照大鼠组织激肽释放酶的变化  

DETECTING THE CHANGES OF RAT TISSUE KALLIKREIN AFTER IRRADIATION BY RIA

作　　者：张皓[1] 乐敏[1] 陈识杰[1] 姜雅梅 胡昱兴[1] 范佩芳 励杏娣[1] 金为翘 

机构地区：[1]上海医科大学放射医学研究所

出　　处：《辐射研究与辐射工艺学报》1990年第4期254-256,共3页Journal of Radiation Research and Radiation Processing

基　　金：国家自然科学基金

摘　　要：采用放射免疫分析法,测定了大鼠经8.5 Gy照射后肾和尿中组织激肽释放酶含量及尿中组织激肽释放酶活力的变化。发现在照后6h受照组肾和尿中组织激肽释放酶的含量显著高于对照组,而在照后72h尿中该酶活力显著低于对照组。Using a direct radioimmunoassay, we examined the changes of tissuekallikrein in rat urine and kidney after a single whole-body 8.5 Gy irradiation. Theenzymatic activity of tissue kallikrein in rat urine was examined. It was found thatthe tissue kallikrein content in kidney and urine of irradiated group were significantlyhigher than control group at 6 h, and the enzymatic activity of tissue kallikrein inrat urine of irradiated group was significantly lower than control group at 72 h.

关 键 词：放射免疫测定 组织 激肽释放酶 

分 类 号：Q556[生物学—生物化学]