止痛灵结构的表征及紫外分光光度法含量测定  

The Structure Characterization of Ethenzamide and Content Determination by UV Spectrophotometry

作　　者：杨魁[1] 李岩[1] 邱方利[1] 

机构地区：[1]台州学院医药化工系,浙江临海317000

出　　处：《安徽化工》2007年第2期62-64,共3页Anhui Chemical Industry

摘　　要：止痛灵粗品经无水乙醇重结晶后,对其进行熔点测定,并用红外光谱及核磁共振谱进行结构表征。经紫外分光光度法检测,止痛灵在无水乙醇中的最大吸收波长为290.5nm,在此波长下测定,止痛灵乙醇溶液工作曲线回归方程为A=0.02033+18686.85643×X,相关系数r=0.9994,吸光系数为а=20547.7,日间平均RSD为0.217%,平均回收率为(100.3±1.03)%。用此方法测定止痛灵,操作简便易行,结果准确,可用于中间体控制和成品检测。Ethenzamide after recrystallization with ethanol,their formula and structure were characterized by melting point determination,IR and HNMR spectroscopy. The ultraviolet spectrophotometry maximum absorption wavelength of tilmicosin Was 290.5 nm,and the regression equation was A=0.02033 ＋18686.85643 xX, r=0.9994,a=20547.7. RSD day average was 0.217% and the average recovery was （100.3±1.025）%. The method is simple and feasible, and the result is reliable. It can be used to determine the product.

关 键 词：止痛灵 紫外分光光度法 含量测定 

分 类 号：O657.32[理学—分析化学]