中青年肾移植患者口服环孢素A与体内5项指标的三维图像对比分析  

Analysis of 3-dimensions images of five indicators in vivo for midaged and younger patients with kidney transplantation administering cyclosporine

作　　者：王弘[1] 尹红[1] 郭绍来[1] 晏学民[2] 

机构地区：[1]中国人民解放军总医院药品保障中心,北京100853 [2]中国矿业大学化学与环境工程学院,北京100083

出　　处：《中国新药杂志》2007年第6期483-484,485,496,I0001,共5页Chinese Journal of New Drugs

基　　金：国家自然科学基金资助项目(30472056)

摘　　要：目的:分析中青年肾移植患者服用环孢素A天数、服药剂量与血药浓度,年龄、血红蛋白与体内红细胞,血糖、钠与钾的三维图像的变化,为临床合理用药提供参考,并研究体内指标与年龄的相关性。方法:将中年与青年肾移植患者的服药剂量、服药天数与年龄、红细胞、血红蛋白、血糖、钾、钠6项指标分为3组,采用MATLAB7.0分析所得三维图像。结果:三维图像显示患者年龄、服用天数与指标存在关系。结论:中、青年患者年龄与服药对体内5项指标有影响。Objective： To investigate the correlation of days and dosage of cyclosporine A （CsA） administered with other blood test outcomes including blood-CsA level, age, levels of Hgb, sodium and potassium, erythrocyte and glycemia in kidney transplantation recipients at the middle and young age. Methods： A retrospective analysis was used to dispose the 3-D correlationship of dosing status （days and dosage） of CsA with other blood test results by a MATLAB 7.0 program. The analytic categories were divided into three groups based on 5 indicators. Results： The 3-D correlationship of age and days of CsA with the other blood test outcomes was found. Conclusion ： The age of administers and administration period of CsA after kidney transplantation were closely impacting other blood test outcomes.

关 键 词：中、青年肾移植患者 三维图像 环孢素A 

分 类 号：R979.5[医药卫生—药品]