枸杞子提取物对大鼠离体胸主动脉舒张作用的初步研究  

Vasodilator Effect of Fructus Lycii Extract on Thoracic Aortic Rings of Rats in Vitro

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作  者:吴维明[1] 冯前进[2] 张立伟[1] 

机构地区:[1]山西大学分子科学研究所,山西太原030006 [2]山西中医学院,山西太原030024

出  处:《山西中医学院学报》2007年第2期18-19,共2页Journal of Shanxi College of Traditional Chinese Medicine

基  金:山西省自然科学基金资助项目(项目编号:20041102)

摘  要:目的:研究枸杞子提取物对大鼠离体胸主动脉的舒张作用。方法:将离体大鼠胸主动脉固定于恒温组织浴槽中,先后加入肾上腺素和枸杞子提取物,记录血管的张力变化。结果:肾上腺素能迅速升高离体大鼠胸主动脉张力,并维持于一定水平,而枸杞子提取物能缓慢地降低离体大鼠胸主动脉张力。结论:枸杞子提取物可抑制肾上腺素所致的离体大鼠胸主动脉收缩。Objective:To observe the vasodilator effect of Fructus Lycii extract on thoracic aortae rings of rats in vitro. Methods:Thoracic aortic rings of rats were put into the constant temperature tissue bath,and were connected to a force transducer by one thread. Then adrenalin and Fructus Lycii extract were added into the bath solution,and the tension of thoracic aortic rings was recorded. Results:The tension of thoracic aortic rings of rats was significantly increased by adrenalin,and was slowly decreased by Fructus Lycii extract. Conclusion:Fructus Lycii extract has vasodilator effect on thoracic aortae rings of rats in vitro.

关 键 词:枸杞子 肾上腺素 舒张作用 

分 类 号:R285.5[医药卫生—中药学]

 

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