中药复方药代动力学常用研究方法评价  

Evaluation of Pharmacokinetic Study Methods of Traditional Chinese Prescription

作　　者：周丽娟[1] 许利平[2] 陈慧娟[1] 白雪[1] 

机构地区：[1]四川省中医药研究院中医研究所,四川成都610031 [2]首都医科大学中医药学院,北京100069

出　　处：《中华中医药学刊》2007年第5期1041-1043,共3页Chinese Archives of Traditional Chinese Medicine

摘　　要：回顾了近年来中药复方药代动力学的常用研究方法,包括生物效应法和血药浓度法,以及国内外学者提出的比较有代表性的各种假设或设想,如“证治药动学”新假说,“复方效应成分动力学”假说,“辨证药动学”假说,“中药胃肠药动学”和“血清药理学”等,客观评价其在研究中药复方药代动力学中的特点。To review the commonly used methods of studying pharmacokinetics of traditional Chinese prescription in recent years which including the methods of studying biological effects and plasma concentration, and all kinds of representative hypothesizes or suppositions proposed by domestic and foreign scholars which including new Hypothesis of ＂Syndrome and Treatment Pharmacokinetics＂, Decoction Effective Components Pharmacokineties Hypothesis,＂ Sydrome Differentiation Pharmacokinetics＂ Hypothesis, gastrointestinal Pharmacokinetics of TCM and Plasma pharmacology, et al. To evaluate objectively their characteristics during pharmacokinetic studies of traditional Chinese prescription.

关 键 词：中药复方 药代动力学 研究方法 生物效应法 血药浓度法 

分 类 号：R286[医药卫生—中药学]