血液粘滞度对血压水平的影响程度  

Effect intensity of blood viscosity on the blood pressure level determination

作　　者：王晓征[1] 聂鑫[1] 彭涛[1] 杨栓锁[1] 张润希[1] 陈涛[1] 

机构地区：[1]郧阳医学院附属东风医院,湖北十堰442008

出　　处：《中原医刊》2007年第7期19-21,共3页Central Plains Medical Journal

摘　　要：目的研究血液粘滞度对血压水平的影响程度。方法将体格检查者2561例作为研究对象,按血压水平将其分为正常血压组和高血压组,正常组1863例,高血压组698例。测量其血压、血糖、血脂、血液流变学的各项指标,用多元线性回归分析血液粘滞度对血压水平的影响。结果高血压组的血糖（GLU）、总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-C）、全血高切粘度（ηbH）、全血中切粘度（ηbM）、红细胞刚性指数（ERI）、红细胞变形指数（TK）等指标均明显高于正常血压组（P〈0.01）,高密度脂蛋白胆固醇（HDL-C）、红细胞聚集指数（EAI）则低于正常血压组（P〈0.01）。多元线性回归显示,血压水平与GLU、TC、TG、LDL-C、ηbm、全血低切粘度（ηbL）、ERI、TK相关。收缩压水平的复相关系数R=0.345,确定系数R2=0.119（F=43.071,P〈0.01）;舒张压水平的复相关系数R=0.331,确定系数R2=0.111（F=39.872,P〈0.01）。结论血液粘滞度通过多种途径影响血压水平,是影响血压水平的一个重要因素,它可以解释大约11%的血压水平的变异。Objective To study of the effect intensity of blood viscosity on the blood pressure level. Methods Two thousand and sixty - one cases according to blood pressure level were divided into the control group（ n = 1863 ） and the EH group（ n = 698）. Collected the material of 2561 cases who attended the physical examination, including blood pressure, plasma lipids, plasma glucose, hemorheology parameters and so on, studied the effect intensity of blood viscosity on the blood pressure level by multiple linear regression analysis. Results GLU, TC, TG, LDL - C, ηbH, ηbM, ERI, TK in the EH group were significantly higher than that of healthy control group（ P 〈 0.01 ） , while the HDL - C, EAI were significantly lower than that of control group （ P 〈 0.01 ）. The results of multiple linear regression showed that correlations were found between the blood pressure level and GLU, TC, TG, LDL - C, ηbM, ηbL, ERI, TK. The multiple correlation coefficient of SBP is R = 0. 345, coefficient of determination is R^2 = 0. 119 （ F = 43. 071 , P 〈 0.01 ）. The multiple correlation coefficient of DBP is R = 0.331 , coefficient of determination is R^2 = 0.111 （ F = 39. 872, P 〈 0.01 ）. Conclusion Blood viscosity can effect the blood pressure level through several pathways, it is an important factor on the blood pressure level and could predict 11% of the variance of blood oressure level.

关 键 词：血液粘滞度 血液流变学 血压水平 多元线性回归 确定系数 

分 类 号：R544[医药卫生—心血管疾病]