急性心肌梗死后左室重构的临床危险因素  

Evaluation of risk factors of left ventricular remodeling after acute myocardial infarction (AMI)

作　　者：周忠泉[1] 周林[2] 易绪英[2] 杨学新[2] 

机构地区：[1]长江大学医学院,湖北省荆州市434000 [2]荆州市第一人民医院心内科

出　　处：《中国心血管病研究》2007年第5期332-333,共2页Chinese Journal of Cardiovascular Research

摘　　要：目的对急性心肌梗死后左室重构的临床危险因素进行评估。方法将进入本观察的51例患者,按溶栓治疗后有无Q波形成,分为Q波组和非Q波组,全部患者入住CCU,并在入院即刻,入院后8、16、24、48、72h分别进行血清心肌酶学检查。对其中34例患者在心梗后1周、6周行超声心动图检查,并测定左室质量指数。结果Q波组血清CPK峰值(1347.58±220.33)IU,左室质量指数分别为234.82±92.36(1周),271.52±93.12(6周)均明显高于非Q波组,随访半年表明新近出现心衰明显高于非Q波组。结论溶栓后的有Q波出现,血清CPK峰值高于500IU,左室质量指数>220g/m3,是急性心肌梗死后左室重构的危险因素。Objective To evaluation the risk factors of left ventricular remodeling after AMI. Methods According to whether there＇s Q-wave formed or not after thromblytic therapy, 51 patients with AMI were divided into Q-wave group and non-Q wave group. They were all admitted to CCU. Their serum myocardial enzymes were tested respectively right after admission and in 8th, 16th,24th,48th and 72nd hour since then. Echocardiography was made and left ventricular mass index （LVMI） was measured among 34 of them in 1 week and 6 weeks after AMI. Results The peak level of CPK was （1347.58±220.33）IU in Q wave group, and its LVMI was 234.82±92.36 in 1 week and 271.52±93.12 in 6 weeks, all these three were much higher than non-Q wave groups. It＇s also found that the incidence of heart failure in Q-wave group was evidently higher than that of non-Q-wave group after half a year following up. Conclusion The present study indicates that Q-wave formed after thromblytic therapy, CPK peak level higher than 500 IU and LVMI more than 220,may be risk factors of left ventricular remodeling after AMI.

关 键 词：心肌梗塞 心室复建 危险因素 

分 类 号：R542.22[医药卫生—心血管疾病]