铁氰化钾-钙黄绿素体系后化学发光反应测定氨基比林  

Flow Injection-Post Chemiluminescence Method for the Determination of Amidopyrine with Calcein-Potassium Ferricyanide System

作　　者：何云华[1] 吕九如[2] 

机构地区：[1]长安大学环境科学与工程学院,西安710054 [2]陕西师范大学化学与材料科学学院,西安710062

出　　处：《分析化学》2007年第4期564-566,共3页Chinese Journal of Analytical Chemistry

摘　　要：研究发现，氨基比林在铁氰化钾-钙黄绿素化学发光反应体系中的后化学发光反应。优化了反应条件，建立了一种利用后化学发光反应测定氨基比林的流动注射化学发光方法。方法的检出限为20μg／L；相对标准偏差为2．0％（2．0mg／L氨基比林，n=11）；线性范围为1．0×10^-4 -1．0×10^-2g／L。此法已用于复方氨林巴比妥注射液中氨基比林含量的测定，结果与药品标准方法测定值一致。A post chemiluminescence （PCL） reaction was observed when amidopyrine was injected into the reaction mixture of potassium ferricyanide-calcein chemiluminescence （CL） reaction system. The experimental conditions of the CL reactions were optimized. A new chemiluminesence method for the determination of amidopyrine with flow injection was developed. The detection limit is 20 μg/L, the relative standard deviation is 2.0% （2.0 mg/L amidopyrine, n = 11 ）, the liner range is 1.0×10^-4 -1.0×10^-2/L. The method has been successfully applied to the determination of amidopyrine in the compound amionprine and antipyrine injection and the results were in good agreement with those obtained by standard method.

关 键 词：后化学发光反应 铁氰化钾 钙黄绿素 氨基比林 热镇痛药 

分 类 号：O657.3[理学—分析化学] R971.1[理学—化学]