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作 者:王慧婷[1] 史凯蕾[1] 朱毅[1] 石文蕾[1]
机构地区:[1]上海市华东医院心内科,200040
出 处:《国际心血管病杂志》2007年第2期141-143,共3页International Journal of Cardiovascular Disease
摘 要:目的:探讨颈动脉粥样硬化与冠心病的关系。方法:根据冠状动脉造影结果将101例病人分为冠心病组及对照组,再根据受累血管数将冠心病组又分为一支病变组、二支病变组及三支病变组。应用高频超声测定所有病例双侧颈总动脉的内-中膜厚度(IMT)、颈总动脉内径,进行分析。结果:冠心病组的左颈动脉的平均IMT为(0.91±0.13)mm,平均内中膜横切面面积(IMCSA)为(22.13±3.21)mm2,而对照组的左颈动脉的平均IMT为(0.84±0.06)mm,平均IMCSA为(18.06±1.15)mm2,两组的差异有统计学意义(P<0.01);冠心病组斑块发生率为63.7%,对照组的斑块发生率为34.6%,差异有统计学意义(P<0.01)。以左颈总动脉IMT0.845mm为界限预测冠心病的敏感性为68.8%,特异性为67.3%;以左颈总动脉IMCSA19mm2为界限预测冠心病的敏感性为87.5%,特异性为84.6%。结论:颈动脉粥样硬化可作为冠心病的预测因子,为临床诊断提供依据。Objective:To observe the relationship between intima-media thickness and carotid artery plaque in coronary heart disease. Methods: 101 patients who had been examined by coronary angiography were divided into normal group (52 patients) and coronary artery disease group(49 patients). Carotid ultrasonography was performed in them. Results: In coronary disease group, the average IMT was (0. 91 ± 0. 13)ram , the average IMCSA was (22. 13 ± 3. 21)mm^2. In normal group, the average IMT was (0.84 ±0.06)mm , the average IMCSA was (18.06 ± 1. 15)mm^2, the difference was significative in statistics. In coronary disease group, carotid artery plague was found in 63.7% of the patients,but it was found in only 34.6% patients in normal group(P〈0.01). To predict coronary disease, if IMT 0. 845mm was served as a separating criterion, the sensitivity was 68.8%, the speciality was 67.3% ; if IMCSA 19mm^2 was served as a separating criterion, the the sensitivity was 87. 5%, the speciality was 84. 6%. Conclusion: Carotid ultrasonography could be used to predict the present coronary heart disease.
关 键 词:颈动脉粥样硬化 颈动脉超声 冠心病 冠状动脉造影
分 类 号:R541.4[医药卫生—心血管疾病]
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