产ESBLs大肠埃希菌的耐药性分析及发展趋势  

Drug-resistance analysis of ESBLs-producing Escherichia coli

作　　者：袁海燕[1] 

机构地区：[1]泰兴市人民医院检验科,江苏泰兴225400

出　　处：《西部医学》2007年第3期455-457,共3页Medical Journal of West China

摘　　要：目的了解产ESBLs(超广谱β-内酰胺酶)大肠埃希菌的耐药情况及发展趋势,为产ESBLs菌的监控和治疗提供依据。方法收集我院三年来门诊及住院患者各类标本中分离的产ESBLs的大肠埃希菌(共144株),采用纸片扩散(K-B)法进行药敏试验。结果产ESBLs菌耐药严重,并且有逐年上升趋势。结论定期进行细菌耐药性的检测,有助于指导临床合理应用抗生素。Objective To understand the drug-resistance condition of ESBLs-producing Escherichia colt （ultrabroad-spectrum β-lactamase） in our hospital as well as its ongoing tendency so as to provide proofs for monitoring and treating ESBLs-producing bacteria. Methods We collected ESBLs-producing Escherichia coll （144 strains） isolated from all kinds of specimens of inpatients and outpatients for 3 years in our hospital and performed drug sensitivity test by paper-diffusion （K-B） method. Results ESBLs-producing bacteria were greatly resistant to drugs with the tendency of going up yearly. Conclusion Periodic assay of the drug-resistance to bacteria will help guide reasonable administration of antibiotics clinically.

关 键 词：Β-内酰胺酶 大肠埃希菌 耐药性 

分 类 号：R454.9[医药卫生—治疗学]