小儿社区获得性肺炎病原学分析  

Analysis of etiology in children with community acquired pneumonia in WenZhou city

作　　者：林加斌[1] 张淑芬[1] 项跃林[1] 张德亭[2] 陈杨芳[2] 

机构地区：[1]浙江省温州市第三人民医院儿科,温州325000 [2]浙江省温州市第三人民医院检验科,温州325000

出　　处：《江西医药》2007年第4期294-296,共3页Jiangxi Medical Journal

摘　　要：目的了解小儿社区获得性肺炎病原学诊断、治疗情况。方法选择2005年10月～2007年2月温州市第三人民医院儿科因CAP住院的患儿146例,取其鼻咽部痰标本进行细菌培养及静脉血清采用间接免疫荧光法检测20项呼吸道病原谱IgM抗体,分析其结果。结果146份标本中阳性标本88份,占60.3%,其中:病毒阳性率43.8%,细菌阳率27.4%,混合感染阳性率11.0%;其中呼吸道合胞病毒(RSV)22例(34.4%),副流感病毒(PIV)19例(29.7%),腺病毒(ADV)16例(25%),柯萨奇病毒(COXV)7例(10.9%),肺炎克雷伯杆菌15例(37.5%),金黄色葡萄球菌10例(25.0%),肺炎链球菌6例(15.0%),大肠埃希菌3例(7.5%),其它绿脓假单胞菌、嗜肺军团菌,副流感杆菌等6例(19.4%)。结论小儿社区获得性肺炎以RSV为主要病原,婴幼儿(尤其1～6个月)病毒感染率最高,好发于冬、春季节。Objective To study the etiology s with community acquired pneumonia （CAP） in children,and provides the basis for the clinial diagnosis and treatment.Methods A prospective study was performed on 146 consecutive young children patients with CAP between Oct 2005 and Feb 2007.Sputum samples were collected for culture,and bacteria were isolated and identified using conventional methods. Antibodies of the paired serum samples to 20 respiratory tract pathogens were detected.Resu/ts The etiology of CAP was identified in 88 （60.3 %） parients.The distribution of causal agents was as follows ： virus in 64 （43.8 %） cases , Bacteria in 39 （26. 7 %）,In 16 patients （11%） more than one causal agent were found,in which, RSV 22 （34.4%）,PIV 19（29.7%）,ADV 16（25%）,COXV 7 （10.9%）, Klebsiella pneumoniae 15 （37.5%）, staphylococcus 10 （25.0%）, streptococcus pneumoniae 6 （15.0%）, Escherichia cob 3 （7.5%） ,others 6 （19.4%）.Conclusion In children,Virus is the most common pathogens in CAP,especially 6-10 months infant.

关 键 词：小儿 社区获得性肺炎 病原学 

分 类 号：R725.6[医药卫生—儿科]