中国南方健康女性跟骨超声骨密度测量评估  

Assessment of low quantitative ultrasound values of calcaneus in Chinese southern healthy females

作　　者：余跃[1] 刘伟[2] 朱自强[2] 徐成丽[2] 朱广瑾[2] 

机构地区：[1]中国医学科学院中国协和医科大学基础医学研究所医学分子生物学国家重点实验室,北京100005 [2]中国医学科学院中国协和医科大学基础医学研究所病理生理学系,北京100005

出　　处：《基础医学与临床》2007年第4期382-385,共4页Basic and Clinical Medicine

基　　金：国家科技部公益性专项基金(2002DIA40018)

摘　　要：目的 了解我国南方地区健康女性跟骨超声骨密度随年龄、身高、体重等变化的规律及骨质疏松患病率的情况，为确定我国南方地区女性超声骨密度的参考值和骨质疏松症的诊断标准提供科学依据。方法 用美国Lunar公司生产的Achilles Express跟骨超声骨密度测定仪，测定2498名年龄在10～87岁的女性跟骨硬度指数（SI），每10岁为一个年龄组，69岁以上合并为1组，共7组，对相关数据进行相应的统计学分析。结果 SI随年龄增长呈现先升后降的变化趋势，骨峰值年龄出现在20～29岁年龄组。Pearson相关分析显示，SI与年龄呈显著负相关，与身高、体重呈正相关。骨质疏松患病率随年龄增加逐步升高。结论 我国南方地区女性硬度指数与年龄、身高、体重均有显著相关性，本研究获得的硬度指数将为确定我国女性超声骨密度的参考值和骨质疏松症的诊断标准提供重要的参考依据。Objective To study the pattern of ultrasonic bone mineral density of calcaneus with age, height and body weight, and to establish a normal reference value of stiffness index （SI） of females in Southern China for providing scientific foundation for osteoporotic diagnosis and prevention. Methods SI for calcaneus in 2498 healthy people 10 - 87 years old was measured with Achilles Express ultrasound apparatus made in USA. They were divided into groups according to sex and age. One group for 10 years each and the records beyond 69 years were classified into one group, total 7 groups. Results The SI showed a characteristic mild rise-then-fall pattern with increasing age. And the peak value of SI presented in 20 - 29 age group. Pearson correlation analysis showed negative correlation between SI and age and a positive correlation between SI/height and weight. The prevalence of osteoporosis gradually increase with age. Conclusion There are significant correlations in SI with age, height and weight; the values of SI will provide an important data reference to establish the normal values and diagnostic standard of osteoporosis.

关 键 词：跟骨 骨质疏松症 定量超声 

分 类 号：R580[医药卫生—内分泌] R445.1[医药卫生—内科学]