阴道毛滴虫吞噬精子过程的超微结构观察  

An Ultrastructural Study on The Process of Spermatozoa Phagocytosis by Trichomonas vaginalis

作　　者：陈文列[1,2] 钟秀容[1,2] 陈金富[1,2] 梁平 蔡蕙珍[1,2] 陈莲云 吴翊钦[1,2] 

机构地区：[1]福建医学院 [2]附属一院妇产科

出　　处：《电子显微学报》1997年第1期15-20,共6页Journal of Chinese Electron Microscopy Society

摘　　要：本文报告应用透射电镜观察体外阴道毛滴虫吞噬、消化人精子全过程的超微结构变化。虫体与精子共育１５～３０ｍｉｎ后，虫体粘附、包绕和吞噬精子，在胞质中形成吞噬泡（食物泡）；共育４５～７５ｍｉｎ，次级溶酶体（消化泡）中的精子被消化；９０～１０５ｍｉｎ后，消化过程结束，细胞质中多见残体（排泄泡）和空泡；１２０～１５０ｍｉｎ，虫体出现自噬现象或摄食。在吞噬与消化精子阶段，虫体的粗面内质网较丰富、高尔基体发达、氢化酶体数量较多。本研究进一步证实阴道毛滴虫具有较强的吞噬与消化的潜在能力。The process of in vitro human spermatozoa phagocytosis and digestion by Trichomonas vaginalis was studied by transmission electron microscopy.After 15—30 minutes of mixed T.vaginalis and sperm incubation,adherion,wrapping and phagocytosis of spermatozoa at the surface of the protozoa were observed,with formation of phagocytic vacuoles.Digestion of spermatozoa in secondary lysosomes occurred after 45—75 minutes incubation,and the digestive process finished with residual bodies and vacuoles foration after 90—105 minutes.Afterward,some protozoa showed autophagic vacuoles,while others engulfed spermatozoa again.The protozoa had plenty rough surfaced endoplasmic reticulum,well developed Golgi complex and many hydrogenosomes during active phagocytosis and digestion.It is indicated that T.vaginalis has powerful capabilities of phagocytosis and digestion,and Trichomonal vaginitis may affect the chance of pregnancy of patient.

关 键 词：阴道毛滴虫 人精子 吞噬 超微结构 

分 类 号：R711.31[医药卫生—妇产科学] R711.602[医药卫生—临床医学]