季节性哮喘患者花粉过敏的临床研究  

Experimental study of pollen-allergens in patients with seasonal asthma

作　　者：殷少军[1] 朱惠如[2] 巫善美[2] 

机构地区：[1]同济大学附属第十人民医院呼吸科,上海200072 [2]复旦大学附属华山医院呼吸科,上海200040

出　　处：《同济大学学报（医学版）》2007年第2期51-53,共3页Journal of Tongji University(Medical Science)

摘　　要：目的探讨季节性哮喘患者花粉过敏的诊断。方法用上海地区常见的4种花粉抗原,分别对季节性哮喘、非季节性哮喘患者及健康成人进行血清特异性IgE(sIgE)测定,并与皮肤挑刺试验(skin prick tests,SPT)、支气管激发试验(bronchial provocation tests,BPT)进行比较。结果季节组sIgE的阳性率明显高于非季节组及健康组(P<0.05);sIgE与SPT及BPT的总符合率分别为82.1%和86.6%。结论测定血清花粉抗原sIgE敏感、安全、简便易行,可作为季节性哮喘花粉过敏的特异性病因诊断方法。Objective To study the etiological diagnosis of the patients with seasonal asthma. Methods In 80 patients with seasonal asthma（40 eases） or non-seasonal asthma（40 eases） and 30 normal healthy individuals,serum specific IgE（sIgE） to four common pollen-allergens in Shanghai area were detected by BSA-ELISA assay, and skin prick tests（SPT）, bronchial provocation tests（BPT）to the same allergens were performed. Results The positive rate of sIgE detemfination in patients with seasonal asthma was significantly higher than that of non-seasonal asthma and normal healthy individuals（P 〈 0.01, P〈 0.05）. The overall correlations between sIgE and SPT, sIgE and BPT were found in 82.1%, 86.6 %, respectively. Conclusion sIgE detected by BSA-ELISA appeared to be a safe and simple method for etiological diagnosis in patients with seasonal asthma,

关 键 词：季节性哮喘 花粉 过敏 诊断 

分 类 号：R562.25[医药卫生—呼吸系统]