记忆合金加压钉抑制山羊半侧脊柱生长的实验研究  

Experimental study on controlling unilateral spine growth by shape memory alloy staple

作　　者：张永刚[1] 张巍[1] 郑国权[1] 张如意[1] 张宏志[1] 王岩[1] 

机构地区：[1]解放军总医院骨科,北京100853

出　　处：《中华外科杂志》2007年第8期537-539,共3页Chinese Journal of Surgery

摘　　要：目的观察记忆合金加压钉置入山羊胸椎侧方对山羊脊柱生长的影响。方法 16只2～3个月雌性山羊,分为单钉组、双钉组和对照组。单钉组6只,经第8肋开胸术显露胸椎,将5枚记忆合金加压钉分别跨越椎间隙置入山羊 T_(6～11)椎体右侧中央,每个椎间隙置入1枚;双钉组6只,实施相同开胸手术,每个椎间隙置入2枚加压钉;对照组4只,进行右侧开胸手术不置入加压钉。每隔1个月拍摄 X 线片,观察脊柱生长情况。结果 X 线观察发现,术后2个月时形成侧凸,单钉组山羊加压节段 Cobb 角12.83°±12.17°;双钉组 Cobb 角12.00°±3.22°。术后4个月时,单钉组侧凸变为6.00°±4.94°,双钉组侧凸增加到25.17°±3.71°。对照组在术后4个月中,未见脊柱形成侧凸畸形。单钉组1只山羊在术后2个月形成15°的后凸畸形,术后4个月时未变化。双钉组1只山羊在术后后凸畸形逐渐增大,4个月时 T_(6～9)节段形成10°的 Cobb 角。结论记忆合金加压钉对半侧椎体进行加压,能够有效抑制半侧脊椎骨骺的生长,调节脊柱生长方向,同时,加压力的大小与脊柱生长抑制成正相关。Objective To observe the effects that shape memory alloy （SMA） staples implanted to the lateral aspect of the thoracic vertebrae on spinal growth in goats. Methods Sixteen goats （ age 2 - 3 months） were divided into 3 groups： six in single staple group; six in double staples group and four in control group. Single staples group underwent right-side thoracotomy for exposing the thoracic spine through the eighth rib. Five SMA staples were placed laterally into vertebral bodies of T6-11 spanning discs. Double staples group underwent the same operation. Laterally directed 10 SMA staples were placed into vertebraes of T6-11 spanning discs and two staple spanning each disc. The last four goats in control groups just only underwent right-side thoracotomy. In the next 4 months after operation, radiographs were taken to observe the spinal growth every month. Results The radiographic analysis demonstrated scoliosis of 12. 83°±12. 17° in single staple group and 12.00°±3.22° in double staple group after 2 months of the operation. Cobb angle of 6.00°±4. 94° and 25. 17°±3.71° were observed in the two groups respectively after 4 months of operation, as compared with 0° in the control groups. Only 2 goats developed kyphosis. Conclusions Compression between vertebral bodies by SMA staples can depress spinal growth in the same side and greater compression result in larger curves.

关 键 词：脊柱侧凸 山羊 记忆合金 加压钉 

分 类 号：R687[医药卫生—骨科学]