在梗阻性黄疸大白鼠中SIL-2的变化  

Change of Hepatic Soluble Intlenkin-2 Receptor Level in Rats with Obstructive Jaundice

作　　者：李炳辉[1] 于忠信[1] 

机构地区：[1]大庆龙南医院普外科,黑龙江大庆163453

出　　处：《黑龙江医药》2007年第3期226-227,共2页Heilongjiang Medicine journal

摘　　要：目的:探讨梗阻性黄疸大白鼠可溶性白细胞介素2受体(SIL-2)的变化。方法:采用胆总管结扎法(BDL)制造大白鼠梗阻性黄疸模型;对照组(Sham)接受同样方法但不结扎胆总管;内引流组在梗阻性三周后行胆肠内引流(ID),动态观察血清SIL-2的变化。结果:ID后SIL-2明显升高,ID1周后SIL-2水平降低。结论:梗阻性黄疸时,机体免疫功能受抑制,内引流可改善机体免疫功能。Objective： To investigate the change of hepatic hepatic soluble intlenkin -2 receptor（ SIL -2R）level, Methads： Obstructive jaundice rat models were estabolished with bile duct ligation （BDL）. Sham operation received the procedure exclusive BDL, BDL for three weeks followed by a second laparotomy and furthure one - week of internal drainage （ID）. The change of hepatic indenkin -2 receptor（ SIL- 2R）level were investigated, Results： serum SIL-2R content obviously increased after BDL, One week of after ID, SIL- 2R decreased . Conclusion： Cellular immunity of obstructive jaundice rats was dispressed and ID could effectively improve host immunity .

关 键 词：梗阻性黄疸 可溶性白细胞介素2受体 

分 类 号：R657.4[医药卫生—外科学]