白芍对膀胱引流式犬胰腺移植Oddi括约肌功能的影响  

The Effect of Radix Paeoniae Alba on Oddi Sphincter of Dogs After Pancreatic Transplantation

作　　者：孙宏治[1] 高丽君[1] 赵国华[2] 付晓光[1] 

机构地区：[1]辽宁医学院附属第一医院普外一科,辽宁锦州121001 [2]辽宁省肿瘤医院胃外科,辽宁沈阳110042

出　　处：《辽宁中医杂志》2007年第5期685-686,共2页Liaoning Journal of Traditional Chinese Medicine

基　　金：辽宁省教育厅2002年度高校科研计划资助项目(202013146)

摘　　要：目的:研究白芍对膀胱引流式犬胰腺移植后移植物Oddi括约肌(SO)功能的影响。方法:正常犬和膀胱引流式胰腺移植后犬应用白芍前后进行SO测压。结果:白芍对正常犬SO收缩幅度无影响(P>0.05),但可降低SO的基础压、收缩频率和动力指数(P<0.01)。移植后应用白芍可全面降低SO基础压、收缩频率、收缩幅度和动力指数(P<0.01)。结论:白芍可抑制犬SO运动,胰腺移植后,抑制作用更加显著,有助于防治移植物胰腺炎。Objective：To investigate the effect of Radix Paeoniae Alba on Oddi sphincter of dogs after pancreatic transplantation. Methods： To measure the pressure of Oddi sphincter for normal dogs and those after pancreatic transplantation. Results： There were no significantly different for contract pressure of normal dogs（ P 〉 0.05 ）, but the basic pressure, contract frequency and motivation index were both droped（ P 〈 0.01 ）. The basic pressure ,contract pressure ,contract frequency and motivation index were all droped when usage of Radix Paeoniae Alba（ P 〈 0.01 ）. Conclusions ： Radix Paeoniae Alba could restrain the movement of Oddi sphincter, which could conduce to prevent and cure the pancreatitis after transplantation.

关 键 词：胰腺移植 ODDI括约肌测压 白芍 

分 类 号：R285.5[医药卫生—中药学]