36例儿童慢性肾功能衰竭病因分析  

ETIOLOGICAL ANALYSIS OF 36 CHILDREN WITH CHRONIC RENAL FAILURE

作　　者：陶于洪[1] 陶庆芬[1] 王峥[1] 

机构地区：[1]四川大学华西第二医院儿科,成都610041

出　　处：《现代预防医学》2007年第9期1640-1641,1645,共3页Modern Preventive Medicine

摘　　要：[目的]探讨儿童慢性肾功能衰竭(Chronic renal failure,CRF)病因。[方法]收集36例CRF患儿性别、年龄、病因、血常规、肾功能和肾脏病理资料并进行统计学分析。[结果]获得性肾小球疾病27例,包括肾病综合征14例和慢性肾炎9例;5例肾脏病理结果:硬化性肾小球肾炎2例、膜增生性肾小球肾炎1例、新月体肾炎1例、毛细血管内增生性肾小球肾炎1例。尿路梗阻5例,肾小管酸中毒3例,多囊肾1例。所有患儿都有贫血,血红蛋白与血肌酐呈负相关(r=-0.516,P﹤0.001)。[结论]儿童CRF的原发病以肾病综合征和慢性肾炎为主。[Objectivel To investigate the etiology of chronic renal failure （CRF） in children. [Methods] The data of the gender, age, etiology, CBC, renal function and renal biopsy in 36 children with CRF were statistically analyzed. [ResultsJ 27 children with CRF were diagnosed as acquired glomerular diseases, including 14 cases of nephritic syndrome and 9 cases of chronic glomerulonephritis. In five kidney pathological reports, there were 2 eases of sclerosis nephritis, 1 case of membranoproliferative glometulonephritis, 1 case of crescentic glomerulonephritis and 1 case of endocapillary proliferative glomerulonephritis. Other diseases were also observed, including 5 cases of urinary tract obstruction, 3 cases of tubercular acidosis and 1 case of polycystic kidney. All patients suffred with anemia, arid a negative relation between the level of hemoglobin and serum creatinine was observed （r =-0.316, P 〈 0.001 ）. [ Conclusion] The main primary diseases of CRF in children are nephritic syndrome and chronic glomerulonephritis .

关 键 词：肾功能衰竭 慢性 病因分析 预防 

分 类 号：R692.5[医药卫生—泌尿科学]