中西药结合治疗弓形虫RH株感染小白鼠疗效的研究  

EFFECT OF COMBINATION CHINESE HERBS AND SULFADIAIINE ON TOXOPLASMOSIS OF MICE

作　　者：方素芳[1] 钟秀会[1] 崔平[2] 张瑞华[2] 

机构地区：[1]河北农大动科院,保定071001 [2]河北北方学院动医系,张家口075000

出　　处：《中国兽医寄生虫病》2007年第3期33-34,共2页Chinese Journal of Veterinary Parasitology

基　　金：河北省教育厅自然基金项目(2003265)

摘　　要：目的观察中西药结合治疗弓形虫RH株感染小白鼠的疗效。方法用弓形虫Rh株感染昆明小鼠,设计复方中药单独治疗组,磺胺嘧啶钠单独治疗组,复方中药与磺胺嘧啶钠联合治疗组及对照组,观察对比各组小鼠存活率和存活天数。结果复方中药与磺胺嘧啶钠联合治疗组小鼠存活率93%、平均存活天数35 d,与其它各组都有显著性差异。结论中西药结合治疗感染弓形虫小鼠的疗效很好。Objective To observe the effect of combination chinese herbs and sulfadiazine on Toxoplasmosis of mice. Methods Mice were infected with RH Toxoplasmagondii, and divided into 4 groups, induding sulfadiazine, dihydroartemisinine and sulfadiazine and control group. The survival rate and survival days of mice was observed and contrasted for from each group. Results The survival rate was 93% and the avevage survival days was 35 days of dihydroartemisinine and sulfadiazine group, there was distinct difference among the four group. Conclusion It was shown that combination chinese herbs and colchicines was effective in the treatment of toxoplasamosis.

关 键 词：复方中药 磺胺嘧啶 弓形虫 小白鼠 疗效 

分 类 号：S852.723[农业科学—基础兽医学]