氟嗪酸在碳纳米管修饰电极上的电化学行为及含量的测定  

Electrochemical Behavior of Ofloxacin at Carbon Nanotubes Film Electrode and Its Voltammetric Determination

作　　者：杨春海[1] 张升晖[1] 刘应煊[1] 黄文胜[1] 

机构地区：[1]湖北民族学院化学与环境工程学院

出　　处：《应用化学》2007年第5期540-545,共6页Chinese Journal of Applied Chemistry

基　　金：湖北省自然科学基金(2004ABA235);湖北省教育厅重点项目(D200629004;D200529004)资助

摘　　要：在玻碳电极上制备了多壁碳纳米管/Nafion(MWNTs-Nafion)膜,用交流阻抗谱(EIS)、循环伏安法(CV)、线性扫描伏安法(LSV)研究了氟嗪酸在该膜上的电化学行为。与裸玻碳电极相比,这种纳米结构膜修饰的电极对氟嗪酸的电化学氧化显现出极好的促进作用,氟嗪酸的氧化峰电流明显增强,在修饰电极上于+0.97 V处产生了1个灵敏氧化峰。LSV测定氟嗪酸的线性范围为1.0×10-8～1.0×10-6mol/L和1.0×10-6～2.0×10-5mol/L,开路富集400 s后,检出限为8.0×10-9mol/L(3倍信噪比),方法可用于人尿中氟嗪酸的实时测定。A multi-wall carbon nanotubes （MWNTs）-Nation film-coated glassy carbon electrode （GCE） was fabricated, and the electrochemical behavior of ofloxacin on the MWNTs-Nafion film-coated GCE was investigated via cyclic vohammetry（ CV）, linearsweep vohammetry（ LSV）, and electrochemical impedance spectroscopy（EIS）. The oxidation peak current of ofloxacin increased significantly at the MWNTs-Nafion film modified GCE, compared with that at a bare GCE. This nano-structured film electrode exhibited excellent enhancement effects on the electrochemical oxidation of ofloxacin. A well-defined oxidation peak attributed to ofloxacin was observed at 0. 97 V and was applied to the determination of ofloxacin. The oxidation peak current was proportional to ofloxacin concentration in the ranges of 1.0 × 10^-8 - 1.0 × 10^-6 mol/L and 1.0 × 10^-6 - 2. 0 ×10^-5 mol/L, and a detection limit of 8.0 × 10^-9 mol/L was obtained for 400 s accumulation at open circuit （S/N = 3 ）. The method was demonstrated via determining ofloxacin in human urine and the result was satisfactory.

关 键 词：氟嗪酸 多壁碳纳米管/Nafion膜 化学修饰电极 溶出伏安法 

分 类 号：O657.1[理学—分析化学]