复合型吸附材料PEI/SiO_2对胆红素的吸附作用  

Adsorption Property of Novel Composite Material PEI/SiO_2 for Bilirubin

作　　者：雷海波[1] 高保娇[1] 申艳玲[1] 

机构地区：[1]中北大学化工系,太原030051

出　　处：《应用化学》2007年第5期580-584,共5页Chinese Journal of Applied Chemistry

摘　　要：通过γ-氯丙基三甲氧基硅烷的偶联,将聚乙烯亚胺(PEI)偶合接枝在硅胶微粒表面,制得了对胆红素具有强吸附性能且可经酸碱处理重复使用的复合型吸附材料。结果表明,PEI大分子链中大量质子化的胺基氮原子与胆红素分子中电离的羧基之间产生的静电相互作用使PEI/SiO2对胆红素有吸附作用。考察了介质pH值、离子强度及PEI在复合材料PEI/SiO2的键合量对胆红素吸附容量的影响。静态吸附实验结果表明,硅胶表面的PEI对胆红素具有强的吸附能力,等温吸附满足Freundlich吸附方程,当胆红素初始质量浓度为0.590 g/L时,平衡吸附量可达13.17 mg/g;在近中性(pH=6)溶液中,复合吸附材料PEI/SiO2对胆红素吸附能力最强;在酸性溶液中,由于胆红素的羧基电离度较小,PEI/SiO2对胆红素的作用力较弱;在碱性溶液中,虽然胆红素的羧基电离度较大,但由于PEI的胺基氮原子质子化程度变小,PEI/SiO2与胆红素之间的作用力较弱。由于静电屏蔽作用,离子强度在很大程度上影响PEI/SiO2对胆红素的吸附容量。Polyethylenimine （PEI） was grafted on silica gel particle surface with γ-chloropropyhrimethoxysilane as the coupling agent, and novel composite adsorption material PEI/SiO2 for biomedical application was prepared. The effect of pH, ionic strength of the medium and the bound amount of PEI on PEI/SiO2 on the adsorption quantity of PEI/SiO2 for bilirubin was examined. The static adsorption experiment results show that PEI/SiO2 has a strong adsorption ability for Bilirubin. The PEI macromolecules on silica particles can produce a strong adsorption effect for bilirubin by means of electrostatic interaction. The isothermal adsorption obeyed the Freundlich equation, and the equilibrium adsorption amount reached 13. 17 mg/g as the preliminary concentration of bilirubin was 0. 590 g/L. The pH value of the aqueous solution has a great effect on the adsorption property of PEI/SiO2. In a near neutral solution （ pH = 6 ）, there was a maximum adsorption amount, and in acidic and basic solutions, the adsorption actions were all weak.

关 键 词：胆红素 吸附材料 聚乙烯亚胺 静电相互作用 吸附作用 

分 类 号：O647.3[理学—物理化学]