中耳三维有限元模型的建立与中耳实体模型质量属性分析  

Reconstruction and analysis of three-dimensional finite element model of human middle ear

作　　者：张官萍[1] 巫爱霞[2] 戴朴[3] 韩东一[3] 陈俊生[4] 韩正理[1] 李永奇[1] 

机构地区：[1]中山大学附属第三医院耳鼻咽喉头颈外科,广州510630 [2]中山大学附属第一医院耳鼻咽喉头颈外科,广州510630 [3]北京解放军总医院耳鼻咽喉科研究所 [4]华南理工大学工程系

出　　处：《中华耳鼻咽喉头颈外科杂志》2007年第5期357-361,共5页Chinese Journal of Otorhinolaryngology Head and Neck Surgery

基　　金：广东省科技计划项目科研基金(2003C30203)

摘　　要：目的根据中国健康人体颞骨组织切片数据建立中耳三维有限元模型,分析中耳腔鼓室各组件的几何尺寸,并通过附带软件计算出各听骨的质量属性。方法根据解放军总医院耳鼻咽喉研究所提供的中国正常人颞骨组织切片数据,采用 AutoCAD2005、UG 软件建立了中耳三维实体模型,在 ADINA 有限元软件中使用手动和自动法对中耳三维实体模型进行网格划分。依据中耳解剖学、声学及生物力学等研究的文献数据对模型进行生理加载和边界约束,建立了包含鼓膜、听骨、韧带、肌肉的中耳三维有限元模型。最后,利用软件附带功能测量出中耳实体模型大小以及质量属性两方面内容,并与已发表的正常中国人中耳解剖结构的测量数据比较验证其结果的几何相似性和可靠性。结果重建了包含鼓膜、听骨、韧带、肌肉的中耳三维有限元模型。从测量中耳实体模型大小以及质量属性两方面的数据证实了此中耳三维有限元模型能良好的模拟正常人体中耳鼓室形态结构,具有良好的几何相似性。结论应用本方法建立的正常人中耳腔三维有限元模型形态逼真,几何相似性好,为进一步的从声学、生物动力学方面测试此模型在不同频率特定声压作用下鼓膜及镫骨的振动反应、中耳传音结构的几何形态及负荷改变奠定了形态学基础。Objective To reconstruct a finite element model of human middle ear and measure characteristic dimensions of this model and calculate the mass properties of the ossicles. Methods The proposed method starts with the histologic section preparation of human temporal bone. Through tracing outlines of the middle ear components on the sections in AutoCAD2005, a set of exterior contours of the components is obtained. The three-dimensional solid model of middle ear, including tympanic membrane, ossicular bones, middle ear suspensory ligaments/muscles, are reconstructed using these contours in Unigraphics （UG）. To prepare for finite element analysis （FEA） of the middle ear, all surfaces of the solid model are translated into ADINA, a commercial FE model package. Based on these surfaces, FE meshes of the middle ear are created, and material properties and boundaries are set up. The characteristic dimensions of this model are measured and the mass properties of the ossicles are calculated to confirm the accuracy of the geometric model constructed following the proposed method. Results The three-dimensional finite element model of the human middle ear that included tympanic membrane, ossicular bones and middle ear suspensory ligaments/muscles was reconstructed. The accuracy of this geometric model was confirmed with the outcome of the characteristic dimensions of this model and the mass properties of the ossicles. Conclusions The proposed method not only provides an effective, convenient, economic, accurate way to reconstruct the three dimensional finite element model of human middle, but also provides a detailed knowledge of middle ear geometry that is required for finite element analysis.

关 键 词：中耳 显微切片术 有限元分析 模型 解剖学 

分 类 号：R764[医药卫生—耳鼻咽喉科]