中长期CPAP治疗阻塞性睡眠呼吸暂停低通气综合征的ESS嗜睡量表评分变化  被引量:4

Epworth Sleepiness Score for Patients with Obstructive Sleep Apnea and Hypopnea Syndrome after Long Term CPAP Treatment

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作  者:黄建浩[1] 李善群[1] 吴晓丹[1] 励雯静[1] 钮善福[1] 白春学[1] 

机构地区:[1]复旦大学附属中山医院肺科,上海200032

出  处:《中国临床医学》2007年第2期165-166,共2页Chinese Journal of Clinical Medicine

摘  要:目的:观察中长期经鼻持续正压通气(nasal continous positive airway pressure,nCPAP)对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的治疗效果及ESS嗜睡量表评分值变化。方法:应用CPAP呼吸机治疗20例OSAHS,并用夜间多导睡眠图及Epworth嗜睡评分量表(ESS)判断CPAP治疗OSAHS的效果。结果:CPAP治疗压力8~12 cmH2O,平均压力为(10.7±1.0)cmH2O。治疗后患者病情明显改善,各种临床不适基本缓解,睡眠时呼吸紊乱指数(AHD由治疗前70.0±40.1降低至治疗后的11.0±5.1(P<0.001),夜间最低血氧饱和度由治疗前的(67.7±10.3)%升高至治疗后(88.6±3.5)%(P< 0.001),氧减饱和指数(ODI4)由治疗前的73.3±34.8降低至治疗后的4.8±2.7(P<0.001),最大血氧氧饱和降低数由治疗前的(28.9±9.4)%降低至治疗后的(9.5±4.1)%(P<0.001),ESS嗜睡量表评分由治疗前的14.9±1.2降低至治疗后的7.0±0.6(P<0.001)。结论:CPAP的应用明显改善夜间气道阻塞,纠正了患者夜间低氧及呼吸暂停,并能减少患者日间嗜睡,从而提高生活质量。Objective: To observe the life quality score about nCPAP treatment of OSAHS. Methods: Twenty patients with OSAHS were treated with nCPAP between July 2002 and Octuber 2005, and noctul PSG monitor and Epworth sleepiness score was used to evaluate the effect of CPAP ventilator on treating OSAS. Results: Work pressure of CPAP was 8- 12 cmH2O, average work pressure of CPAP was 10.7 ± 1.0 cmH20,CPAP can improve the symptom of OSAS. After treatment,AHI decreased from 70.0 ± 40. 1 to 11.0 ± 5. 1(P〈0. 001) ;the lowest SaO2 increased from (67.7 ± 10.3)%to (88.6 ± 3.5) (P〈0. 001),ΔSaO2 decreased from(28.9 ± 9.4) to (9.5 ± 4.1) % (P〈0. 001 ) ,ODI4 decreased from(73.3 ± 34.8) to (4. 8 ± 2.7) (P〈0. 001 ), ESS decrease from 14.9 ± 1.2 to 7.0 ± 0.6(P〈0. 001 ). Condusion: CPAP can improve airway obstruct, treatment effect is good.

关 键 词:阻塞性呼吸暂停低通气综合征 经鼻持续正压通气 多导睡眠图 Epworth嗜睡评分'口…“l-’n… 

分 类 号:R56[医药卫生—呼吸系统]

 

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