^(18)F-FDG PET/CT和增强CT对胰腺病变定性诊断的价值比较  

The value of combining ^(18)F-FDG PET/CT and CECT in differential diagnosis of malignant and benign pancreatic lesions

作　　者：胡荣剑[1] 姚稚明[2] 潘纪戍[1] 李伟[2] 韩丽君[2] 周诚[1] 屈婉莹[2] 

机构地区：[1]卫生部北京医院放射科,100730 [2]卫生部北京医院核医学科,100730

出　　处：《中华核医学杂志》2007年第2期68-72,共5页Chinese Journal of Nuclear Medicine

摘　　要：目的评价^(18)F-脱氧葡萄糖(FDG)PET/CT 对胰腺良、恶性病变定性诊断的价值。方法对15例胰腺恶性病变,6例良性病变患者行全身^(18)F-FDG PET/CT 和增强 CT 检查,根据 PET、增强 CT和 PET/CT 图像上的表现分别诊断,并将结果进行比较。结果 PET 和 PET/CT 准确诊断全部恶性病变,而增强 CT 准确诊断全部良性病变。PET 和 PET/CT 在6例良性病变诊断中分别显示2例和1例假阳性,而增强 CT 在15例恶性病变中有2例假阴性,但在上述3种诊断方法中分别出现的假阳性或假阴性都得到了相互间的纠正。增强 CT、PET 和 PET/CT 三者在诊断胰腺恶性肿瘤上的准确性分别为90.5%,90.5%和95.2%。此外,PET/CT 比增强 CT 检出了更多的肝脏、淋巴结和骨转移灶;两者检出病灶数量分别为35,41,9和16,24,3个。结论 PET/CT 在胰腺良、恶性病变定性诊断上有价值,PET/CT 和增强 CT 联合应用有利于进一步提高对胰腺恶性肿瘤的诊断和分期准确性。Objective Pancreatic lesion is still a clinical challenge in spite of many imaging technology advances. For better diagnosis, investigation in this study was the values of combining ,^18F-fluorodeoxyglucose （FDG） PET/CT and abdominal contrast-enhanced CT （CECT）in malignant and benign pancreatic lesions. Methods The whole body ^18F-FDG PET/CT and abdominal CECT were performed in 15 patients with malignant pancreatic lesions and 6 benign lesions. The diagnoses were made by PET, CECT alone and PET/CT respectively. The diagnostic value of each strategy was reviewed in light of pathologic findings. Results All malignant pancreatic lesions were accurately diagnosed by PET and PET/CT, while CECT correctly identified all benign lesions. Among 15 patients with malignant pancreatic lesions, 2 were false negative in CECT, while 2 false positive in PET and 1 false positive in PET/CT were encountered among 6 patients with benign lesions. The diagnostic accuracy of CECT, PET and PET/CT in malignancies were 90.5% ,90.5% and 95.2%, respectively. PET/CT detected more metastases lesions in liver, lymph nodes and bone （35, 41 and 9, respectively） than CECT （ 16, 24 and 3, respectively）. Conclusion The combination of PET/CT and CECT could enhance the accuracy in differential diagnosis and staging of pancreatic tumors.

关 键 词：胰腺肿瘤 体层摄影术 发射型计算机 体层摄影术 X线计算机 脱氧葡萄糖 

分 类 号：R817.4[医药卫生—影像医学与核医学]