精神分裂症中医分型治疗的生化研究  

Biochemical Study on TCM Treatment of Schizophrenia Based on Syndrome Typing

作　　者：张良栋[1] 周刚[1] 金宗余 林友光 徐声汉[1] 周龙标[1] 许家驹[2] 肖亮[2] 陈圣祺[2] 葛小锚[2] 邬建民[2] 路长林[3] 王成海[3] 黄爱军[3] 

机构地区：[1]上海市精神卫生中心,上海宛平南路600号200030 [2]上海市杨浦区精神卫生中心 [3]第二军医大学神经生物学教研室

出　　处：《中医杂志》1997年第3期173-175,共3页Journal of Traditional Chinese Medicine

摘　　要：123例精神分裂症分为痰火内扰型、阴虚火旺型、痰湿内阻型、阳虚亏损型,各型分为中西医结合辨证治疗组66例和以西药任选治疗组57例。临床观察、量表分分析及3年后随访结果,均说明辨证治疗组疗效优于西药任选组。病人的β-EP在痰湿内阻和阳虚亏损两型的含量,经治疗后均由低而升高,NT在痰火内扰型中的含量,经治疗后则由高而趋于正常,而在阴虚火旺、痰湿内阻和阳虚亏损三型中的含量,经治疗后均显著上升。说明辨证分型治疗有一定生化变化基础。One - hundred twenty - three cases of schizophrenia were classified as the following types: inner disturbance by phlegmatic fire ( IDPF) , exuberant fire due to yin-depletion ( EFYD) , inner obstruction of phlegmatic dampness (IOPD) and Yang depletion (YD). Sixty - six cases were treated as integrated Chinese and western medicine group (66 cases) and western drug group (57 cases). Observation by dose - score table analysis and 3- year following exam all showed that the results of integrated group was superior to the western drug group. The contents of β - EP in IOPD and YD types were increased from sub - normal level after therapy. The contents of NT in IDPF group was dropped to normal after treatment; while that in the other 3 groups were all distinctively increased, demonstrating that there was biochemical basis for the treatment based on syndrome typing.

关 键 词：精神分裂症/中医药疗法 辨证论治 

分 类 号：R277.793[医药卫生—中医学]