南岭前胡素A的结构鉴定  

ISOLATION AND STRUCTURE ELUCIDATION OF LONGSHENGENSIN A FROM PEUCEDANUM LONGSHENGENSE

作　　者：黄平[1,2] 郑学忠[1,2] 西正敏 中西勤 

机构地区：[1]广西中医药研究所 [2]日本摄南大学药学部

出　　处：《药学学报》1997年第1期62-64,共3页Acta Pharmaceutica Sinica

摘　　要：从前胡属新种植物南岭前胡（ＰｅｕｃｅｄａｎｕｍｌｏｎｇｓｈｅｎｇｅｎｓｅＳｈａｎｅｔＳｈｅｈ）根中首次分离得到２个单体化合物，经理化常数、波谱数据解析，分别鉴定为南岭前胡素Ａ（Ｉ）和甘露醇（ＩＩ）。晶Ｉ为一新化合物，通过和凯林内酯的化学沟通确定其绝对构型，化学结构为（－）３′（Ｓ）乙酰氧基４′（Ｓ）当归酰氧基３′，４′二氢邪蒿内酯。Two compounds were isolated from Peucedanum longshengense Shan et Sheh for the first time. Their structures were identified as longshengensin A (I) and mannitol (II) by physico chemical constants and spectral analyses (UV,IR,MS,NMR and 2D NMR). I is a new compound with the structure of (-) 3′( s ) acetyloxy 4′( s ) angeloyloxy 3′,4′ dihydroseselin and named longshengensin A. Its absolute configurations were determined by chemical correlation with khellactone.

关 键 词：南岭前胡 南岭前胡素A 鉴定 

分 类 号：R284.1[医药卫生—中药学]