α-硫辛酸对糖尿病周围神经病变的疗效  

Efficacy ofα-lipoic acid in treating diabetic peripheral neuropathy

作　　者：宋利格[1] 李颖[1] 周筠[1] 陈亚青[1] 李红[1] 张秀珍[1] 

机构地区：[1]上海同济大学附属同济医院内分泌科,200065

出　　处：《中华内分泌代谢杂志》2007年第2期166-167,共2页Chinese Journal of Endocrinology and Metabolism

摘　　要：选择40例2型糖尿病并发糖尿病周围神经病变(DPN)患者分别静脉注射α-硫辛酸和甲钴胺连续2周,发现α-硫辛酸可以提高DPN患者神经传导速度,同时降低尿微量白蛋白、血浆内皮素和C反应蛋白,具有显著疗效,并且其疗效与甲钴胺相仿。Forty type 2 diabetic patients with diabetic peripheral neuropathy （DPN） were assigned to two groups and treated respectively with α-lipoic acid or mecobalamin for 2 weeks. The results suggested that α-lipoic acid could accelerate the nerve conduction velocity and decrease the plasma level of endothelin and C reactive protein as well as microalbuminceria with a effect similar to mecobalamin therapy on DPN.

关 键 词：硫辛酸 糖尿病神经病变 神经传导 

分 类 号：R587.2[医药卫生—内分泌]