妇科手术后预防下肢深静脉血栓形成对患者凝血功能的影响  

The effect of prophylactic for lower extremity deep vein thrombosis on blood clotting of patients after gynecological surgery:a prospective study

作　　者：杨柏柳[1] 张震宇[1] 郭淑丽[1] 

机构地区：[1]首都医科大学附属朝阳医院妇产科,北京100020

出　　处：《现代妇产科进展》2007年第4期278-280,共3页Progress in Obstetrics and Gynecology

基　　金：首都医学发展科研基金资助项目(No:2005-1005);"十五"攻关肺栓塞规范化诊疗方法基金项目(No:2004BA703B07)

摘　　要：目的研究采取下肢间歇性气囊加压(IPC)与低分子肝素(LMWH)等预防措施对妇科盆腔手术后下肢深静脉血栓形成高危患者凝血功能的影响。方法前瞻性随机对照研究96例妇科手术后有下肢深静脉血栓(DVT)危险因素的患者,使用IPC与LMWH预防后,分析血常规、凝血功能、血栓相关指标及血栓发生率的变化。结果应用IPC与LMWH预防后,抗凝血酶-III(AT-III)较术前显著升高(P<0.05),LMWH使术后血小板水平明显下降(P<0.05)。结论预防性使用IPC与LMWH可以改善妇科盆腔手术后患者的凝血功能,降低深静脉血栓的形成率。Objective： To study the effect of lower extremity deep vein thrombosis （DVT） prophylactics intermittent pneumatic compression （IPC） and low-molecular-weight heparin （LMWH） on blood clotting in DVT high risk patients after gynecological surgery . Method：This propective randomized case-control study consisted of ninty-six postoperative patients with high risk of DVT,ICP and LMVH were used as prophylactics for DVT,and the change of blood routine, coagulation function and morbidity of DVT were analyzed. Result： AT-Ⅲ was higher than pre-operation in patients using IPC and LMWH （ P 〈 0.05 ）, and PLT was lower in patients using LMWH （ P 〈 0.05 ）. Conclusion ： Coagulation funtion can be improved by using IPC and LMWH after gynecological surgeries, postoperative DVT can be decreased.

关 键 词：血栓深静脉形成 妇科外科手术 预防和控制 凝血功能 

分 类 号：R713[医药卫生—妇产科学]