应用生物羊膜填塞缝合固定术治疗偏中心角膜穿孔  

Biological amnion plugging to treat the meta-central corneal perforation

作　　者：王晶[1] 王旭[1] 张华[1] 刘文[1] 韩芳菊[1] 冯文国[1] 韩旭光[1] 

机构地区：[1]济南市第二人民医院眼科,济南250001

出　　处：《中国实用眼科杂志》2007年第5期527-529,共3页Chinese Journal of Practical Ophthalmology

基　　金：济南青年科技明星计划（2005-115）

摘　　要：目的探讨生物羊膜填塞缝合固定术治疗偏中心角膜穿孔的疗效。方法应用生物羊膜制作成羊膜塞,对9例偏中心角膜穿孔患者行羊膜填塞缝合固定联合羊膜覆盖术治疗。其中,真菌性角膜溃疡穿孔2例,陈旧性病毒性角膜炎角膜白斑穿孔4例,角膜异物取出术后穿孔3例。结果9眼术后早期无羊膜塞脱出或脱入前房,覆盖的羊膜移植片透明完整,未见溶解和脱落,真菌性角膜溃疡者术后7～10天炎症控制稳定,溃疡消失,角膜穿孔愈合,前房形成。4周内均形成完好的角膜上皮覆盖,羊膜塞与周边角膜组织愈合良好。术后三个月随访显示,羊膜塞位置正常,无排斥或向前房内脱落,穿孔瘢痕愈合形成角膜翳,角膜透明度正常。视力由术前的0.02-0.1提高到0.5-1.0。验光检查：-0.25±0.47D。结论生物羊膜填塞缝合固定术治疗角膜穿孔是一种取材容易,操作简单,行之有效的治疗方法。Objective To discuss the treatment efficiency of the biological amniotic membrane plugging to treat the meta-central corneal perforation. Methods The biological amnion were rolled to be a biological bysma. This bysma was used to plugging the meta-central corneal perforation on 9 patients, Including 2 fungal keratitis perforations, 4 old herpes simple keratitis leucoma perforations and perforations after removal corneal foreign body. Results At the early stage after the surgery, no amniotic bysma prolapsed or took off into the anterior chamber, fungal corneal ulcer recovered during 7-10days, The corneal perforation turned to be scaring healed. The anterior chamber were well-form.The corneal epithalium covered well. Three monthes postoperatively,the amniotic bysma were normotopia,no rejection and prolapsed.The cornea were clearity. The visual acuity raised to 0.5-1.0 from 0.02-0.1. Conclusions Biological amniotic membrane plugging is a security, easy-operated and effectivity method to treat the meta-central corneal perforation.

关 键 词：角膜穿孔 生物羊膜 填塞 

分 类 号：R683.05[医药卫生—骨科学]